Recurrent Thyrotoxicosis and Papilledema in a Patient With Communicating Hydrocephalus

Ophthalmologic manifestations in headache, neurologic deficits, and cerebrospinal fluid lymphocytosis (HaNDL) syndrome with nonspecific frontal lesions and hyperthyroidism

“…Although the precise aetiology of the association remains obscure, the tonic pupils in this case could be related to an autoimmune disease.Thus far, no clear causal link has been established between Hashimoto's disease and cerebrospinal fluid lymphocytosis, although hyperthyroidism is known to cause increases in intracranial pressure. 10 The aetiology of HaNDL is unknown but an inflammation such as an allergic response after an infection or an autoimmune disease is more likely rather than an infection because of the noninfectious profile that is seen on cerebrospinal fluid analysis, the lack of fever, and a normal serum complete blood count. Autoimmune disorders might be one of causative factors of HaNDL.…”

“…9,10 We report a case of slow growing choroidal melanoma that led to a circumscribed intraconal orbital extension that was managed successfully by a combined approach of enucleation and orbitotomy.…”

Headache and Tremor: Co-occurrences and Possible Associations

“…In one, ICP was within the normal range 57. Two of these patients were also diagnosed with communicating hydrocephalus,56,57 and in a third slight dilation of ventricles was noted 58. It is possible that raised ICP in these patients was caused by decompensation of pre-existent CSF circulation abnormalities, as proposed by Herwig.…”

“…Raised ICP and an altered threshold to migraine have been proposed 54,55. There are several case reports on patients with symptoms of increased ICP that appear to be caused by hyperthyroidism 56–59. Next to tremor and other features attributable to hyperthyroidism, patients experienced headache and vomiting and showed signs of raised ICP, such as papilledema.…”

Intracranial Hypertension in a Patient with a Chiari Malformation Accompanied by Hyperthyroidism

“…Coutinho et al 2) showed a case of 31-year-old woman with clinical symptoms and laboratory confirmation of Graves' disease that presented as pseudotumor cerebri. Stern et al 15) showed a case of 29-year old woman who had headache and laboratory confirmation of Graves' disease with occult hydrocephalus that became symptomatic during episode of thyrotoxicosis. Herwig et al 5) showed a case of 32-year-old woman presenting with progressive symptoms of IICP and slight enlargement of the ventricle on CT scan.…”