Recurrent Thromboembolism with Spontaneous Platelet Aggregation

Scrobohaci, Marie-Lorraine; Cunescu, V; Orha, I

doi:10.1055/s-0038-1648086

Cited by 5 publications

(1 citation statement)

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“…In both cases, PTG and platelet life-span were within normal limits, and in one of them MDA levels were slightly elevated. Spontaneous aggregation has been reported in patients suffering from cerebral ischemic attacks, angina, diabetes mellitus, and in recurrent deep-vein thrombosis [9][10][11][12][13]. However, the incidence of SPA found in this study is similar to that found by Hoogendijk et a1 [ 131 in a normal population.…”

Section: Discussionsupporting

confidence: 80%

Platelet activity in mitral valve prolapse: A study of platelet aggregation, malondialdehyde production, and plasma β‐thromboglobulin

et al. 1985

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Platelet aggregation, malondialdehyde (MDA) production, and recovery after aspirin (ASA) administration and plasma levels of beta-thromboglobulin (BTG) were determined in 40 asymptomatic patients with mitral valve prolapse (MVP) and 17 normal subjects. Platelet aggregation was similar in patients and controls, although two patients presented spontaneous aggregation. Production of MDA and plasma levels of BTG were higher in MVP than in controls; however, recovery after ASA was similar in both groups. The results further indicate that platelet hyperactivity is present in a significant number of asymptomatic patients with MVP.

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Section: Discussionsupporting

confidence: 80%