Recurrent reactive angioendotheliomatosis in pregnancy: a case report

Saif, Ghada A. Bin; Buraik, Mohammed A.; Pokharel, Apar; Sangüeza, Omar P.

doi:10.1111/ijd.13014

Cited by 5 publications

(4 citation statements)

References 13 publications

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“…Therefore, no specific treatment is used. It is usually managed by treating the underlying systemic disorder but recurrences remain possible [ 15 , 16 ]. Systemic steroids have been used [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Reactive Angioendotheliomatosis in Association with Ulcerative Colitis

Afiouni,

Abadjian,

Stephan

2024

Case Reports in Dermatological Medicine

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Reactive angioendotheliomatosis (RAE) is a rare benign skin condition characterized histologically by the proliferation of dermal vessels and endothelial cells that occurs secondary to an underlying disease such as infections or lymphoproliferative disorders. To our knowledge, no previous cases of RAE associated with ulcerative colitis (UC) were reported in the literature. Therefore, we report the case of a 46-year-old man with a history of UC presenting with RAE confirmed on histopathology and immunostaining.

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Section: Discussionmentioning

confidence: 99%

Reactive Angioendotheliomatosis in Association with Ulcerative Colitis

Afiouni,

Abadjian,

Stephan

2024

Case Reports in Dermatological Medicine

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“…Antibiotics for occult infections and systemic steroids for their suppressive effect on neoangiogenesis have also been used in cases where no apparent underlying aetiology has been found. Some cases can resolve spontaneously (Bin Saif et al, 2015). This diagnosis should be based on the clinical-pathological correlation, rather than the pure morphology of the cells involved (Enzinger & Weiss, 1983).…”

Section: Discussionmentioning

confidence: 99%

“…The capillaries are lined by hypertrophic endothelial cells filled with several red blood cells. Bar = 200 and 100 μm.lateral, and ventral aspects of the fish; moreover, most of the ponds were adequately shaded.One of the investigated animals (case #4) was treated with dexamethasone; the use of dexamethasone in human patients may have played a role in vascular regulation and the disappearance of the cutaneous lesions in some cases(Bin Saif et al, 2015). Regarding the pharmacological effect of dexamethasone,Katychev et al (2003) demonstrated that pericytes, in particular, undergo apoptosis in response to this corticosteroid, suggesting that the regulatory function of this steroid may be important in vascular development and that pericyte apoptotic cell death may accompany vascular regression.…”

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confidence: 99%

Cutaneous angiomatosis‐like presentation in koi carp (Cyprinus carpio koi): Clinical–pathological investigations

Mandrioli

Barbè²,

Foselli³

et al. 2023

Journal of Fish Diseases

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Koi carps (Cyprinus carpio koi) are an ornamental fish variety frequently kept as pets in domestic ponds worldwide (Ott Knüsel et al., 2016). Fish diseases usually arise from a complex interaction of a variety of factors. The majority of problems affecting ornamental fish have multifactorial causes involving stress as a result of poor husbandry, poor water quality, overcrowding, and overfeeding. In a closed water system, such as a pond or aquarium, water quality analysis is an important procedure. The routine investigation should involve checking levels of ammonia, nitrite, nitrates, and pH; additional parameters such as hardness and dissolved oxygen may be required in some circumstances (Wildgoose, 2001). As an example of environmental causes of disease related to the pond, sunburn causes petechiation and patches of erythema on white and non-pigmented dorsal surfaces of exposed fish, and often occurs in shallow ponds where there is no shade and the water is exceptionally clear.

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“…A large number of skin tumours may cause pain (69). The most relevant differential diagnostic considerations to painful CLMs are shown in Table II (3,30,(69)(70)(71). Although the clinical spectrum of CLMs is broad, many of these tumours can readily be eliminated as likely differential Definitive criteria set a firm diagnosis.…”

Section: Differential Diagnosesmentioning

confidence: 99%

Hereditary Leiomyomatosis and Renal Cell Cancer

Hansen¹,

Chayed²,

Pallesen³

et al. 2020

Acta Derm Venerol

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Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an inherited tumour predisposition syndrome. Around 75% of individuals with HLRCC develop cutaneous leiomyomas, which are skin tumours that can cause pain and itching. Most women with HLRCC develop uterine leiomyomas that often cause gynecological symptoms and typically require surgery. Around 20% develop renal cell carcinoma. HLRCCassociated renal cell carcinomas are aggressive tumours with a high potential to metastasize. Individuals with features suggestive of HLRCC and at-risk family members should undergo genetic testing. Individuals harbouring a pathogenic mutation should be offered lifelong surveillance so renal neoplasms are detected and treated in time. Hereditary leiomyomatosis and renal cell cancer is a genodermatosis with an autosomal dominant inheritance pattern. It is a tumour predisposition syndrome characterized by cutaneous and uterine leiomyomas, and increased susceptibility to develop renal cell carcinoma. There are 200-300 families with hereditary leiomyomatosis and renal cell carcinoma reported worldwide, but the syndrome is believed to be underdiagnosed. Cutaneous leiomyomas are small smooth muscle tumours that tend to grow over time. Larger lesions, in particular, can cause pain or itching. Uterine leiomyomas have a high penetrance in women with hereditary leiomyomatosis and renal cell cancer. They frequently cause symptoms, and surgical intervention is often necessary. Hereditary leiomyomatosis and renal cell cancer-associated renal cell carcinomas have a high potential to metastasize. Patients are diag nosed by genetic testing if a pathogenic mutation is demonstrated in the gene encoding fumarate hydratase. Immunohistochemistry may be a useful diagnostic approach in patients without a detectable pathogenic mutation. Diagnosed patients should be monitored for renal tumours in a lifelong surveillance programme.

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Recurrent reactive angioendotheliomatosis in pregnancy: a case report

Cited by 5 publications

References 13 publications

Reactive Angioendotheliomatosis in Association with Ulcerative Colitis

Reactive Angioendotheliomatosis in Association with Ulcerative Colitis

Cutaneous angiomatosis‐like presentation in koi carp (Cyprinus carpio koi): Clinical–pathological investigations

Hereditary Leiomyomatosis and Renal Cell Cancer

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