Recurrent priapism in the young patient treated with baclofen

Moreira, Daniel Martins; Pimentel, Marcelo; Moreira, Bernardo Ferreira da Silva; Stein, Airton Tetelbom; Koff, Walter José

doi:10.1016/j.jpurol.2005.11.009

Cited by 8 publications

(7 citation statements)

References 9 publications

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“…While baclofen is commonly used to relief the pain symptoms of SRPE patients, in those with primary disease it is not ideal (13). Clinical studies by Van Driel and Moreira et al (40,44) found that the use of monoamine oxidase inhibitors, benzodiazepines, tricyclic antidepressants, and selective serotonin reuptake inhibition alleviated symptoms of SRPE to varying degrees. Other researchers also believe that combination therapy should be the primary treatment strategy for SRPE (10).…”

Section: Combination Therapymentioning

confidence: 99%

Narrative review: pathogenesis, diagnosis, and treatment of sleep-related painful erection

Wang¹,

Zhang²,

Liu³

2021

Transl Androl Urol

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Objective: Through critical analysis and comprehensive review of the limited literature, this paper can help clinicians better identify the pathophysiology of sleep-related painful erections (SRPE) and provide direction for future treatment research.Background: Patients with SRPE will be awakened by painful erections during sleep, which affects their sleep process and general health. At present, literatures of experimental and clinical research on SRPE disease are limited, as well as long-term reports on its pathogenesis and clinical management. Methods: We use the PubMed database to obtain sleep-related peer erection literature. The search terms used include sleep, painful, penis and erection. After rigorous screening, the search returned 21 references published between 1987 and 2021. Conclusions: The main cause of SRPE is obstructive sleep apnea (OSA) syndrome, psychological and spiritual factors, androgen elevation, neuroendocrine regulation and threshold of pain in the REM phase.The combination of multiple medications is the most effective approach to treat sleep-pain-related erections.The combination of CPAP, REM inhibitors and Baclofen has significant effect on SRPE caused by OSA syndrome. This article provides effective support and strategies for doctors to manage SRPE patients through a comprehensive analysis of the pathogenesis mechanism and clinical treatment strategies of SRPE.

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Section: Combination Therapymentioning

confidence: 99%

Narrative review: pathogenesis, diagnosis, and treatment of sleep-related painful erection

Wang¹,

Zhang²,

Liu³

2021

Transl Androl Urol

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“…Bu hastaların 30'unda tedavide internal pudendal arter embolizasyonu denenmiş ve %80 başarı sağlanmıştır. 40,41 Non-iskemik priyapizm tedavisinde, alfa adrenerjik enjeksiyon tedavisinin, sistemik dolaşıma geçebi-leceği için yeri bulunmamaktadır.…”

Section: Non-i̇skemi̇k Pri̇yapi̇zmunclassified

Priapism in Children: Review

Yücel¹,

Uçar²,

Kozacıoğlu³

2017

J Reconstr Urol

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“…terbutaline) have success rates !62% in adults; their mechanism of action of is unclear; aadrenergic effects are postulated. Baclofen, a gammaaminobutryric acid (GABA) receptor inhibitor is reported to have treated priapism successfully in a few children [48], typically with spinal cord injury; however, its side-effect profile (drowsiness, nausea and ED) limits its use.…”

Section: The Management Of Stuttering Priapismmentioning

confidence: 99%