Recurrent preeclampsia and perinatal outcome: a study of women with recurrent preeclampsia compared with women with preeclampsia who remained normotensive during their prior pregnancies

Mendilcioğlu, İnanç; Trak, Bilal; Üner, Mine; Umit, Selda; Küçükosmanoğlu, Mesut

doi:10.1111/j.0001-6349.2004.00424.x

Cited by 15 publications

(16 citation statements)

References 14 publications

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“…Consequently, the increased risk for pre-eclampsia in women with prior late cesarean delivery could be explained by the presence of pre-eclampsia in the Wrst pregnancy. Previous authors have established that pre-eclampsia in previous pregnancy is a risk factor for preeclampsia and other adverse pregnancy outcomes in subsequent pregnancies [24][25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Previous cesarean section, gestational age at first delivery and subsequent risk of pre-eclampsia in obese mothers

Mbah

Sharma

Alio

et al. 2011

Arch Gynecol Obstet

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Section: Discussionmentioning

confidence: 99%

Previous cesarean section, gestational age at first delivery and subsequent risk of pre-eclampsia in obese mothers

Mbah

Sharma

Alio

et al. 2011

Arch Gynecol Obstet

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“…88 If not previously prescribed, low-dose aspirin may be initiated in such women. 89 Because women with previous preeclampsia are at increased risk for adverse outcomes (preterm delivery, fetal growth restriction, abruptio placentae, and fetal death) 25,26,90 in subsequent pregnancies, we recommend they receive more frequent prenatal visits than what is recommended for normal pregnancy. Beginning at 20 weeks of gestation, we recommend office visits every 2 weeks until 32 weeks and then every week thereafter.…”

Section: Management Of Women Who Have Had Preeclampsia In Prior Pregnmentioning

confidence: 99%

Prediction and Prevention of Recurrent Preeclampsia

Barton

Sibai

2008

Obstetrics &Amp; Gynecology

274

182

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Women with a history of previous preeclampsia are at increased risk of preeclampsia and other adverse pregnancy outcomes in subsequent pregnancies. The magnitude of this risk is dependent on gestational age at time of disease onset, severity of disease, and presence or absence of preexisting medical disorders. The objective in the management of these patients is to reduce risk factors by optimizing maternal health before conception and to detect obstetric complications as early as possible. This objective can be achieved by formulating a rational approach that includes preconception evaluation and counseling, early antenatal care, frequent monitoring of maternal and fetal well-being, and timely delivery. First-trimester ultrasound examination is essential for accurate dating and establishing fetal number. Laboratory studies are obtained to assess the function of different organ systems that are likely to be affected by preeclampsia and to establish a baseline for future assessment. Recent studies have confirmed that there is no single biomarker that can be clinically useful for the prediction of recurrent preeclampsia. Combinations of biomarkers and biophysical parameters appear promising, but more data are needed to confirm their use in clinical practice. Supplementation with fish oil, calcium, or vitamin C and E and the use of antihypertensives have been shown to be ineffective in the prevention of recurrent preeclampsia and are not recommended. Supplementation with low-dose aspirin may be offered on an individualized basis. Because women with previous preeclampsia are at increased risk for adverse pregnancy outcomes (preterm delivery, fetal growth restriction, abruptio placentae, and fetal death) in subsequent pregnancies, we recommend more frequent monitoring for signs and symptoms of severe hypertension or preeclampsia than that recommended for normal pregnancy. This monitoring may include more frequent prenatal visits, home blood pressure monitoring, or nursing contacts. For patients with a prior pregnancy complicated by preeclampsia with fetal growth restriction, we recommend serial ultrasound evaluation of fetal growth and amniotic fluid volume. The development of severe gestational hypertension, fetal growth restriction, or recurrent preeclampsia requires maternal hospitalization.

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“…Pre‐eclampsia, whether a first or a recurrent episode, is a major cause of maternal and fetal morbidity and mortality 7,8 . It is reported that women with recurrent pre‐eclampsia have an increased rate of perinatal loss compared with women who have had a prior normotensive pregnancy 9 …”

Section: Introductionmentioning

confidence: 99%

“…Secondary analysis of studies of aspirin for the prevention of pre‐eclampsia suggested that the rate of preterm delivery, abruptio placentae and fetal death was higher in women with a previous episode of pre‐eclampsia compared with nulliparous women 1 . Another group has compared women with recurrent pre‐eclampsia with women who developed pre‐eclampsia after having been normotensive in earlier pregnancies and found a worse perinatal outcome 9 . We designed the present retrospective study to compare perinatal outcome in women with recurrent pre‐eclampsia with that of nulliparous women who have pre‐eclampsia.…”

Section: Introductionmentioning

confidence: 99%

Perinatal outcome of recurrent pre‐eclampsia versus pre‐eclampsia in nulliparas

Chen¹,

Kao

et al. 2009

J of Obstet and Gynaecol

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Recurrent preeclampsia and perinatal outcome: a study of women with recurrent preeclampsia compared with women with preeclampsia who remained normotensive during their prior pregnancies

Abstract: Women with recurrent preeclampsia had a higher rate of perinatal loss compared to women with preeclampsia who were normotensive in their prior pregnancies.

Cited by 15 publications

References 14 publications

Previous cesarean section, gestational age at first delivery and subsequent risk of pre-eclampsia in obese mothers

Previous cesarean section, gestational age at first delivery and subsequent risk of pre-eclampsia in obese mothers

Prediction and Prevention of Recurrent Preeclampsia

Perinatal outcome of recurrent pre‐eclampsia versus pre‐eclampsia in nulliparas

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