Recurrent Pleomorphic Adenoma of the Parotid Gland

Leonetti, John; Marzo, Sam J.; Petruzzelli, Guy J.; Herr, Brian

doi:10.1016/j.otohns.2005.04.008

Cited by 52 publications

(47 citation statements)

References 16 publications

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“…When it occurs, recurrence of pleomorphic adenoma is often difficult to treat since satellite nodules are common. Multiple satellite nodules and previous dissection increase the risk of facial nerve injury [12,13]. In recurrent pleomorphic adenoma, treatment involves revision parotidectomy with an attempt to spare the facial nerve when it is not infiltrated by tumor.…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma of the parotid gland in children

Rodriguez

Vargas

Robson

et al. 2007

International Journal of Pediatric Otorhinolaryngology

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Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma of the parotid gland in children

Rodriguez

Vargas

Robson

et al. 2007

International Journal of Pediatric Otorhinolaryngology

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“…4,5 However, several investigations have shown a good prognosis for cases of CEPA with minor extracapsular invasion, although there is confusion about the threshold between minor and wide extracapsular invasion. 4,6,[10][11][12] Also, there is no information about the prognosis of CEPA associated with primary PA compared with that of CEPA associated with recurrent PA. [13][14][15][16] We therefore decided to investigate a large series of cases of CEPA in which we could: correlate survival with the stages of histological progression; determine the threshold of extracapsular invasion where minor invasion becomes wide invasion with regard to prognosis; and compare the prognosis of CEPA associated with primary PA with that of CEPA associated with recurrent PA.…”

Section: Introductionmentioning

confidence: 99%

Carcinoma ex pleomorphic adenoma with special reference to the prognostic significance of histological progression: a clinicopathological investigation of 41 cases

et al. 2011

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Aims: To investigate a large series of cases of carcinoma ex pleomorphic adenoma (CEPA) to determine prognostic factors. Methods and results: Thirty cases of CEPA associated with primary pleomorphic adenoma (PA) and 11 cases of CEPA associated with recurrent PA were investigated. The median follow-up was 57.7 months, and ranged from 4 to 156 months. Purely intraductal carcinoma was found in 15 cases. Intraductal and extraductal intracapsular carcinoma together was found in one case. Extracapsular carcinoma was found in 25 cases. Prognosis was good for CEPA that was purely intraductal, extraductal intracapsular, or up to 5 mm extracapsular, and poor for CEPA that was 8 mm or more extracapsular. There were relatively more cases of CEPA with extracapsular invasion of 8 mm or more from recurrent PA than from primary PA, and the prognosis for CEPA associated with recurrent PA was worse than that for CEPA associated with primary PA. Conclusions: The threshold for distinguishing minor extracapsular invasion with good prognosis from wide extracapsular invasion with poor prognosis is 5 mm. The worse prognosis for CEPA associated with recurrent PA indicates the necessity for close surveillance of patients with recurrent PA.

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“…It is of paramount importance to ensure the removal of every bit of epithelium in the cavity to avoid a recurrent cholesteatoma. The stapes superstructure is removed, because leaving it behind could allow fat to exert a pistonlike pressure on the stapes or frank subluxation, leading to postoperative vertigo . The closure of the ET is an important step, and it must be done meticulously to prevent an opening.…”

Section: Discussionmentioning

confidence: 99%