Recurrent pericarditis in children and adolescents

Abstract

Recurrent pericarditis has an overall favourable prognosis in children, although it may require frequent readmissions and seriously affect the quality of life, especially in patients treated with corticosteroids. Colchicine or anakinra therapies were associated with significant decrease in the risk of recurrence.

Pediatric Pericarditis Case Report

“…However, a 2016 systematic review demonstrated a lack of evidence to support or discourage the use of colchicine in pediatric pericarditis (Alabed, P erez-Gaxiola, & Burls, 2016). Furthermore, a multicenter cohort study done by Imazio et al (2016) demonstrated a significant decrease in the risk of recurrence of pericarditis, whereas the use of corticosteroids in adults has been associated with an increased risk of recurrence (Seferovi c et al, 2013). Recurrence of pericarditis in children ranges from 15% to 40% (Shakti et al, 2014).…”

Idiopathic recurrent pericarditis — a paradigm shift?

“…Помимо вышеперечисленных изменений, в исследованиях M. Raatikka, A. Brucato, и M. Imazio описаны также такие симптомы и синдромы, как выпот в полость плевры у 36-56% пациентов и повышение аминотрансфераз в 8% случаев [33,34]. По данным нашего исследования у 20 пациентов с ИРП выпот в полость плевры выявлен в 80% случаев, а повышение аминотрансфераз в 50%, что не укладывается в представление о классическом течении перикардита (табл.…”

The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges

“…Similar to adults, a number of children with IRP have been treated successfully with anakinra (6, 31, 32). The anakinra dose was 100 mg/day for adults (30, 33, 34) and 1–2 mg/kg/day (up to 100 mg/day) for children (3, 31, 33).…”