Recurrent Pericarditis

I Diretriz Brasileira de Miocardites e Pericardites

“…A colchicina tem demonstrado ser efetiva como terapêutica coadjuvante da pericardite aguda, no alívio da dor e na prevenção da recorrência ao fim de dezoito meses 220,227 . A dose é de 0,5 mg de 12/12 horas ou 0,5 mg a cada 24 horas nos pacientes com menos de 70 kg, pelo período de três meses no primeiro evento e 6 meses na pericardite recorrente 228,229 .…”

Acute idiopathic pericarditis: current immunological theories

“…6 Some experts advocate that, once collagen vascular disease, previous cardiac surgery, or myocardial infarction are ruled out, relapsing pericarditis is probably immune-mediated with or without a viral trigger. 4,5,7,[11][12][13][14] Pericardial biopsy is not widely used. 4,5,7 IRAP has a benign prognosis, 1,10-13 thus an invasive approach is often not undertaken, at least in the majority of patients.…”

“…4,5,7,[11][12][13][14] Pericardial biopsy is not widely used. 4,5,7 IRAP has a benign prognosis, 1,10-13 thus an invasive approach is often not undertaken, at least in the majority of patients. 4,5,7 However, the main drawbacks of such a conservative approach are that: (1) etiology and pathogenesis of IRAP remain controversial, (2) viral etiology is often suspected, but not proven, and its role as a trigger or precipitating factor in IRAP remains undefined.…”

“…6,14 The most commonly reported specif ic etiologies include tuberculosis (3.9%-4.7%), neoplastic pericarditis (4.7%-7%), and autoimmune disease (1.7%-10.2%). [1][2][3][4][5][6][7][8][9][10][11][12][13][14] Acute pericarditis is presumed to be idiopathic and/or viral in 80%-90% of the cases in immunocompetent patients from developed countries. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] Immune-mediated pericarditis may include: allergic (eg, drug-related), autoimmune (IRAP, postmyocardial injury syndromes, and pericarditis associated with systemic autoimmune disease), and autoinflammatory forms (eg, pericarditis in association with familial Mediterranean fever) ( Table 1).…”

“…[2][3][4][5][6][7][8] Recurrent acute pericarditis is generally idiopathic or postcardiac injury, and is often a frustrating disease, for both patients and physicians. [2][3][4][5][6][7] Idiopathic recurrent acute pericarditis (IRAP) is a disease of suspected, yet unproven, immune-mediated pathogenesis. IRAP should not be confused with a pericarditis associated with systemic autoimmune or immune-mediated disorders; all known causes of pericarditis should be excluded.…”