Recurrent pannus formation causing prosthetic aortic valve dysfunction: Is excision without valve re-replacement applicable?

Darwazah, Ahmad K.

doi:10.1186/1749-8090-7-62

Cited by 12 publications

(7 citation statements)

References 9 publications

(17 reference statements)

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“…Non-neoplastic aortic root pathologies include aortic valve pannus of the prosthetic valve and leaflet thrombus. Pannus is a diffuse or mass-forming inflammatory process often originating from a suture [61]. The fibrotic proliferation can often occur on the ventricular side and appear as a focal round hypodensity [62].…”

Section: Tumors and Tumor-like Conditions At The Aortic Rootmentioning

confidence: 99%

Imaging of the aortic root on high-pitch non-gated and ECG-gated CT: awareness is the key!

et al. 2020

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The aortic pathologies are well recognized on imaging. However, conventionally cardiac and proximal aortic abnormalities were only seen on dedicated cardiac or aortic studies due to need for ECG gating. Advances in CT technology have allowed motionless imaging of the chest and abdomen, leading to an increased visualization of cardiac and aortic root diseases on non-ECG-gated imaging. The advances are mostly driven by high pitch due to faster gantry rotation and table speed. The high-pitch scans are being increasingly used for variety of clinical indications because the images are free of motion artifact (both breathing and pulsation) as well as decreased radiation dose. Recognition of aortic root pathologies may be challenging due to lack of familiarity of radiologists with disease spectrum and their imaging appearance. It is important to recognize some of these conditions as early diagnosis and intervention is key to improving prognosis. We present a comprehensive review of proximal aortic anatomy, pathologies commonly seen at the aortic root, and their imaging appearances to familiarize radiologists with the diseases of this location.

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Section: Tumors and Tumor-like Conditions At The Aortic Rootmentioning

confidence: 99%

Imaging of the aortic root on high-pitch non-gated and ECG-gated CT: awareness is the key!

et al. 2020

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“…Some reported that pannus formation causing prosthetic aortic valve stenosis occurred mainly in female patients with a small BSA (10,11). Histologically the pannus is an overgrowth of fibrous tissue which composed by myofibroblasts, endothelial cells, chronic inflammatory cells and an extracellular matrix such as collagen fiber (12).…”

Section: Commentsmentioning

confidence: 99%

Aorta-atria-septum combined incision for aortic valve re-replacement

et al. 2018

J. Thorac. Dis.

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This case report illustrates a patient who underwent supra-annular mechanical aortic valve replacement then suffered from prosthesis dysfunction, increasing pressure gradient with aortic valve. She was successfully underwent aortic valve re-replacement, sub-annular pannus removing and aortic annulus enlargement procedures through combined cardiac incision passing through aortic root, right atrium (RA), and upper atrial septum. This incision provides optimal visual operative field and simplifies dissection.

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“…Besides, the opening and closure of the prosthetic heart valve might be restricted because of pannus formation and/or thrombosis formation, leading to both prosthetic valve dysfunction and stenosis. Pannus formation is a proliferation of fibro-elastic tissue and collagen due to the body’s inflammatory reaction to the valve prosthesis, which occurs in the tissue–valve interface and creeps along the suture lines, leading to prosthetic valve stenosis or SAS in the LVOT [ 16 , 17 ]. The average rate of prosthetic heart valve dysfunction ranges between 10% and 30% at 10 years of implantation [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic Performance of Dysfunctional Prosthetic Heart Valve with the Concomitant Presence of Subaortic Stenosis: In Silico Study

et al. 2020

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The prosthetic heart valve is vulnerable to dysfunction after surgery, thus a frequent assessment is required. Doppler electrocardiography and its quantitative parameters are commonly used to assess the performance of the prosthetic heart valves and provide detailed information on the interaction between the heart chambers and related prosthetic valves, allowing early detection of complications. However, in the case of the presence of subaortic stenosis, the accuracy of Doppler has not been fully investigated in previous studies and guidelines. Therefore, it is important to evaluate the accuracy of the parameters in such cases to get early detection, and a proper treatment plan for the patient, at the right time. In the current study, a CFD simulation was performed for the blood flow through a Bileaflet Mechanical Heart Valve (BMHV) with concomitant obstruction in the Left Ventricle Outflow Tract (LVOT). The current study explores the impact of the presence of the subaortic on flow patterns. It also investigates the accuracy of (BMHV) evaluation using Doppler parameters, as proposed in the American Society of Echocardiography (ASE) guidelines.

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Recurrent pannus formation causing prosthetic aortic valve dysfunction: Is excision without valve re-replacement applicable?

Cited by 12 publications

References 9 publications

Imaging of the aortic root on high-pitch non-gated and ECG-gated CT: awareness is the key!

Imaging of the aortic root on high-pitch non-gated and ECG-gated CT: awareness is the key!

Aorta-atria-septum combined incision for aortic valve re-replacement

Hemodynamic Performance of Dysfunctional Prosthetic Heart Valve with the Concomitant Presence of Subaortic Stenosis: In Silico Study

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