Recurrent ovarian malignancy presenting as cutaneous metastasis

Abstract

Cutaneous metastasis from ovarian carcinoma is relatively uncommon in clinical practice. We report the case of the woman who presented to us with clitoral nodules and skin nodules. Histopathological examination of nodules confirmed the diagnosis of metastasis of an ovarian carcinoma. Despite poor prognosis, the patient responded and survived well beyond the expected four months survival of similar cases.

Clitoral priapism due to distant clitoral metastasis of high-grade serous ovarian carcinoma: A case report and review of the literature

“…Case reports of clitoral metastases include patients with a retroperitoneal leiomyosarcoma as well as bladder, breast, renal, stomach, cervix, uterus and anorectal carcinomas ( Cokmert et al, 2014 ; Julien et al, 2012 ; Filho et al, 2014 ). One report by Karpate et al reports a patient with probable ovarian adenocarcinoma presenting with a recurrence as clitoral and skin nodules ( Karpate et al, 2009 ). The only cases involving gynecologic malignancies are patients with cervical and uterine cancers; to our knowledge there have been no reported cases of clitoral metastasis on primary presentation of ovarian cancer or metastasis due to high-grade serous carcinoma of the ovary.…”

Solitary cutaneous metastasis from an ovarian high‐grade serous carcinoma at the initial presentation: Cytologic diagnosis of a rare manifestation

“…Therefore, establishing a prompt definitive diagnosis in such cases is imperative for better patient outcomes 3,4 . The majority of the published reports of skin metastasis from ovarian malignancies have been diagnosed by histopathologic examination of the skin lesions, and there is scarce literature on the cytologic diagnosis of cutaneous metastasis in ovarian cancer 5,6 …”

Sister Mary Joseph Nodule in an Ovary Adenocarcinoma

“…However, cutaneous metastasis from ovarian carcinoma is relatively uncommon in clinical practice (2). Here we report a case of SMJN in a 54-year old female patient presented at Dermatology Department, Clinical Center of The University of Sarajevo.…”

“…Sister Mary Joseph Nodule (SMJN) is a metastatic umbilical lesion secondary to a primary malignancy of any viscera, stomach and colon being most common in men, and ovary in women ( 1 ). However, cutaneous metastasis from ovarian carcinoma is relatively uncommon in clinical practice ( 2 ). Here we report a case of SMJN in a 54-year old female patient presented at Dermatology Department, Clinical Center of The University of Sarajevo.…”