Recurrent Orbital Cholesterol Granuloma

Ong, Lorraine Y.; McNab, Alan A.

doi:10.1080/01676830701377252

Cited by 12 publications

(5 citation statements)

References 10 publications

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“…2 Orbitofrontal cholesterol granulomas have been associated with trauma as miniscule as a bee sting, 3 and have been shown to recur after incomplete excision. 3–5 Some of these have been reported to exhibitc evidence of dysplasia of the adjacent bone, suggesting a pre-existing bony or vascular anomaly as a possible etiology. 6 Renal cholesterol granulomas were thought to be associated in separate cases with hypercholesterolemia or atheromatous cholesterol emboli and epithelioid angiomyolipoma.…”

Section: Discussionmentioning

confidence: 99%

Cholesterol granuloma of the anterior mediastinum with osseous metaplasia

Ezzat

Alowami

2012

Rare Tumors

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Cholesterol granuloma is a well-characterized entity comprised of a foreign-body giant cell-reaction that forms in response to the presence of cholesterol crystals. It is usually found in the middle-ear or mastoid process in patients with diseases associated with chronic inflammation such as cholesteatoma and otitis media. They are rarely seen in the mediastinum. Osseous metaplasia is an exceedingly rare feature of cholesterol granulomas only reported twice in the literature. We report a case of a cholesterol granuloma of the anterior mediastinum with osseous metaplasia in a 75 year-old man that was found incidentally during urgent coronary artery bypass graft surgery.

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Section: Discussionmentioning

confidence: 99%

Cholesterol granuloma of the anterior mediastinum with osseous metaplasia

Ezzat

Alowami

2012

Rare Tumors

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“…Orbital inflammatory conditions are considered to be either infectious or noninfectious in origin and originate from neighboring tissue such as the nasal or paranasal sinuses, oral cavity, tooth root, ocular surface, or intraocular structures. Orbital infections typically form granulomas, 39 abscesses, 24 or cellulitis 40 and are a result of bacterial, 41 fungal, 42 or parasitic infections, 43 as well as penetrating foreign bodies 44 . Significant periocular swelling, pain on retropulsion of the globe and oral manipulation is typically noted on clinical examination.…”

Section: Discussionmentioning

confidence: 99%

Surgical management of orbital nodular granulomatous episcleritis in a dog

Barnes

Pearce

Berent

et al. 2010

Veterinary Ophthalmology

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A 27 kg, 6-year-old, male castrated German shorthaired pointer presented to the University of Missouri, Veterinary Teaching Hospital with the complaint of progressive exophthalmia of 2 years duration optical density (OD). Lack of retropulsion OD was noted on physical examination. Anterior segment examination OU and fundic examination OS did not reveal any abnormalities. Examination of the fundus OD revealed focal scleral indentation of the inferior nasal globe. The indentation changed location with globe movement OD. MRI and CT scan revealed a well-circumscribed, approximately 2 cm in diameter mass located caudal and ventral to the affected globe that appeared to communicate with the nictitating membrane with absence of any bony involvement. A modified lateral orbitotomy was recommended and performed to remove the orbital mass and nictitating membrane en-bloc. Histopathology and immunohistochemistry of the mass confirmed a diagnosis of nodular granulomatous episcleritis (NGE). Postoperatively, the dog developed absolute keratoconjunctivitis sicca (KCS). Examples of primary episcleral inflammation in the dog include diffuse episcleritis, NGE, nodular fasciitis, fibrous histiocytoma, proliferative conjunctivitis/keratoconjunctivitis, pseudotumor, and Collie granuloma. The etiology of these episcleral inflammations is presumed to be immune mediated. To our knowledge, this is the first report of NGE affecting the orbital region of a dog. Development of absolute KCS resulting from excision of the nictitating membrane is also supported by this case.

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“…[3][4][5] Some of these have been reported to exhibitc evidence of dysplasia of the adjacent bone, suggesting a pre-existing bony or vascular anomaly as a possible etiology. 6 Renal cholesterol granulomas were thought to be associated in separate cases with hypercholesterolemia or atheromatous cholesterol emboli and epithelioid angiomyolipoma. 7,8 In the breast, the inciting event was postulated to be duct ectasia or periductal inflammation.…”

Section: Discussionmentioning

confidence: 99%

“…The imaging findings of these masses are not specific to cholesterol granuloma and may simulate different entities, both baleful and benign. Such mimics include dermoid cyst, 6 pancreatic cystic neoplasms, 12 craniopharyngioma, renal cell carcinoma,8 breast cancer and invasive thymic neoplasm. The unfortunate consequence of this is that unnecessary, potentially harmful interventions could be performed for this ultimately benign entity.…”

Section: Discussionmentioning

confidence: 99%

Cholesterol Granuloma of Chest Wall – A very Rare Benign Tumour

Nine¹,

Haider²,

Ahmed³

et al. 2020

Cardiovasc. j.

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Cholesterol granuloma is a rare benign tumour and is described as inflammatory granulation that occurs in response to the deposition of cholesterol crystals. It is found most commonly in the paranasal sinuses or temporal bones, but there are also rare reports of their occurrence in the peritoneum, parotid gland, lymph nodes, thyroglossal duct, kidney, liver, and spleen. Involvement of the ribs has rarely been described previously. We report a case of cholesterol granuloma involving chest wall in second intercostals space of a 74-year-old male who presented with a slowly growing lesion of the anterior aspect of right side of the chest. Cardiovasc. j. 2020; 12(2): 158-161

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Recurrent Orbital Cholesterol Granuloma

Cited by 12 publications

References 10 publications

Cholesterol granuloma of the anterior mediastinum with osseous metaplasia

Cholesterol granuloma of the anterior mediastinum with osseous metaplasia

Surgical management of orbital nodular granulomatous episcleritis in a dog

Cholesterol Granuloma of Chest Wall – A very Rare Benign Tumour

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