Recurrent Nonmenstrual Toxic Shock

Cone, Lawrence A.; Byrd, Richard G.; Schulz, K; Schlievert, Patrick M.

doi:10.1086/324365

Cited by 1 publication

(2 citation statements)

References 5 publications

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“…Furthermore, the intermittent pattern of diarrhoea was a clue to target SEC since, in several reported cases of SEC, there is an association between toxic shock syndrome toxin-1 (TSST-1) and staphylococcal enterotoxins or even the isolated identification of TSST-1. The latter is involved in the pathogenesis of staphylococcal toxic shock syndrome (TSS), whose recurrence has been reported in previous studies [10][11][12]. Therefore, even in the absence of criteria for TSS -probable and definitive -the presented case's recurrent nature weighed on the investigation's continuance.…”

Section: Investigationsmentioning

confidence: 66%

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Staphylococcal Enterocolitis: An Atypical Clinical Presentation of a Neglected Disease

Paes Leme,

Pinheiro,

Pereira

et al. 2024

Preprint

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S. aureus is an alarming human pathogen since it triggers numerous diseases, including impetigo and pneumonia. The S. aureus' ability to colonise the upper respiratory tract and other tissues, such as the skin, throat and gut, operate as reservoirs for infection. Indeed, being a carrier of S. aureus in the gut represents a risk factor for developing infection in distinct sites, including an unusual gastrointestinal tract disease. Here, we present an atypical clinical course of staphylococcal enterocolitis (SEC) in a man in his early seventies. After an unforeseen identification of methicillin-resistant Staphylococcus aureus (MRSA), the oral administration of vancomycin was critical in the outcome of the case. Although infrequent, SEC is an underestimated disease and requires a chapter in the treatment recommendations for antibiotic-related diarrhoea. Awareness of the risk factors and diagnostic tests, along with including SEC in algorithms for handling antibiotic-associated diarrhoea, is a step towards new epidemiological information.

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Section: Investigationsmentioning

confidence: 66%

“…Most cases of SEC present acutely with non-specific symptoms such as fever, vomiting and abdominal pain, plus large-volume, "cholera-like" diarrhoea [10][11][12]. When measured, stool volumes can be several litres daily, with over eight litres/day recorded in one study [9].…”

Section: Discussionmentioning

confidence: 99%