In this paper, a new speech enhancement method is proposed and is based on the application of the Wiener filtering in the Bionic Wavelet Transform (BWT) domain. The BWT provides a time-frequency selectivity and better energy concentration property. The proposed method was compared to a number of speech enhancement methods including a BWT based speech enhancement method, Wiener filtering ,and MMSE-STSA. Results are evaluated objectively using signal-to-noise ratio (SNR), segmental signal-to-noise ratio (segSNR), Itakura-Saito distance (ISd) and perceptual evaluation of speech quality (PESQ) with TIMIT sentences corrupted by various noise types and SNRs. The obtained results show that the proposed method gives good results when compared to the other techniques.