Recurrent meningitis in the pediatric patient—the Otolaryngologist’s role

Drummond, Denis S.; Jong, A.L. de; Giannoni, Carla M.; Sulek, Marcelle; Friedman, Ellen M.

doi:10.1016/s0165-5876(99)00022-1

Cited by 60 publications

(60 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For this review, in accordance with most other authors (1,42,44), we defined recurrent bacterial meningitis as two or more episodes of meningitis caused by a different bacterial organism or, alternatively, a second or further episode caused by the same organism with a greater-than-3-week interval after the completion of therapy for the initial episode. In addition, we included cases with two or more episodes of bacterial meningitis defined by abnormal CSF results if the episodes occurred a minimum of 3 weeks apart.…”

Section: Definition Of Recurrent Bacterial Meningitismentioning

confidence: 99%

Epidemiology, Etiology, Pathogenesis, and Diagnosis of Recurrent Bacterial Meningitis

2008

View full text Add to dashboard Cite

SUMMARY Recurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity.

show abstract

Section: Definition Of Recurrent Bacterial Meningitismentioning

confidence: 99%

Epidemiology, Etiology, Pathogenesis, and Diagnosis of Recurrent Bacterial Meningitis

2008

View full text Add to dashboard Cite

show abstract

“…Recurrent bacterial meningitis accounts for 1 to 6% of meningitis cases acquired in the community (4,92,95,303). Conditions associated with recurrent meningitis are age dependent.…”

Section: Recurrent Bacterial Meningitismentioning

confidence: 99%

Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis

2010

View full text Add to dashboard Cite

SUMMARY The epidemiology of bacterial meningitis has changed as a result of the widespread use of conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the significant morbidity and mortality associated with bacterial meningitis, accurate information is necessary regarding the important etiological agents and populations at risk to ascertain public health measures and ensure appropriate management. In this review, we describe the changing epidemiology of bacterial meningitis in the United States and throughout the world by reviewing the global changes in etiological agents followed by specific microorganism data on the impact of the development and widespread use of conjugate vaccines. We provide recommendations for empirical antimicrobial and adjunctive treatments for clinical subgroups and review available laboratory methods in making the etiological diagnosis of bacterial meningitis. Finally, we summarize risk factors, clinical features, and microbiological diagnostics for the specific bacteria causing this disease.

show abstract

“…However, the rate may be lower in children. In a study by Drummond et al, [8] conducted on pediatric meningitis patients during a ten-year period, the rate of recurrent meningitis has been observed to be only 1.3%. In another study conducted in a tertiary pediatric training and research hospital in Turkey, a rate as high as 6.2% has been observed for recurrent meningitis, [9] which is higher compared to the previous studies.…”

Section: Discussionmentioning

confidence: 98%