Recurrent ischemic stroke in a patient with ulcerative colitis and high levels of lipoprotein (a)

Calabrò, Rocco Salvatore; Pezzini, Alessandro; Gervasi, Giuseppe; Pollicino, Patrizia; Bramantı, Placido

doi:10.1097/mbc.0b013e3283485fc5

Cited by 4 publications

(1 citation statement)

References 12 publications

(13 reference statements)

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“…Patent foramen ovale, paradoxical embolism from peripheral venous system, embolization from thrombi formed within the atrial septum, intracardiac thrombi as a result of arrhythmias, and inherited and secondary thrombophilia are considered important stroke risk factors [11]. However, there are other uncommon causes of thrombosis [12,13]. Specifically, it is known that aPL is causatively related to the clinical manifestations of APLS, and are not merely innocent markers of aPL related ischemic stroke [1,2].…”

Section: Discussionmentioning

confidence: 99%

New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

et al. 2019

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Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation.

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Section: Discussionmentioning

confidence: 99%

New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

et al. 2019

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Cerebral arterial infarction in inflammatory bowel diseases

Katsanos¹,

Kosmidou²,

Giannopoulos³

et al. 2014

European Journal of Internal Medicine

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Cerebral sinovenous thrombosis in a child with ulcerative colitis

Liu¹,

Ren

Zhou³

et al. 2020

Medicine

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Rationale: Cerebral sinovenous thrombosis (CVT) associated with inflammatory bowel disease (IBD) is infrequent, but clinically nonnegligible due to its high disability and fatality rates. Patient concerns: A 12-year-old child with newly developed ulcerative colitis (UC) suffered from a sudden left-sided hemiparesis and numbness. Diagnoses: Cerebral sinovenous thrombosis due to ulcerative colitis was diagnosed in this girl. Interventions: The patient was treated with blood transfusion and anticoagulation therapy. Digital subtraction angiography (DSA) and urokinase thrombolysis were implemented followed. Outcomes: The patient achieved a complete recovery of limb functions and did not present any other stroke recurrences at follow-up a year later. Lessons: CVT in UC is a serious condition and can occur in the children and adolescents. Rapidly diagnosis of this complication of IBD and apply anticoagulant therapy early can contribute to avoiding a potentially fatal outcome.

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Recurrent ischemic stroke in a patient with ulcerative colitis and high levels of lipoprotein (a)

Cited by 4 publications

References 12 publications

New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

Cerebral arterial infarction in inflammatory bowel diseases

Cerebral sinovenous thrombosis in a child with ulcerative colitis

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