Recurrent intracranial haemorrhage in Behcet disease.

Nagata, Kensei

doi:10.1136/jnnp.48.2.190

Cited by 14 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The angiographic features suggest an intimal tear during the development of an aneurysm. [133][134][135] There are also reports of parenchymal haemorrhage [136][137][138][139][140] ; in one series, there was one haemorrhage in the brainstem and two in the caudate 137 ; another involved the cerebellum. 138 An inflammatory lesion may be complicated by haemorrhage within; in one a lesion evolved to become haemorrhagic and the second had a series of haemorrhagic lesions associated with inflammation within the cortices on both sides.…”

Section: Aneurysmmentioning

confidence: 99%

See 1 more Smart Citation

Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome

Kidd

2023

Pract Neurol

View full text Add to dashboard Cite

Neurological involvement in Behçet’s syndrome arises predominately through an inflammatory meningoencephalitis characterised by perivenular inflammation due to activation of Th-17 immunological pathways. The brainstem is involved in 50% of cases, the diencephalon and other areas of the brain in 30%, and the spinal cord in 10%. Movement disorders and epilepsy may occur. Psychiatric syndromes may arise with brain and brainstem involvement, and cognitive disorders relate to the brain disease, to circulating inflammatory factors, and to fatigue and despondency. Eighty per cent of cases begin with a relapsing disease course, of whom 70% have only one attack, and 30% have a progressive disease course either from onset or following an initially relapsing course. Venous thrombosis leading to intracranial hypertension and cerebral venous infarction is less common and caused by inflammation in affected veins and a circulating prothrombotic state. Arterial involvement is rare and relates to an arteritis affecting large-sized and medium-sized vessels within the brain leading to infarction, subarachnoid and parenchymal haemorrhage, aneurysm formation and arterial dissection. There is a newly recognised disorder of cerebral cortical hypoperfusion. Cranial neuropathy, peripheral neuropathy and myositis are rare. There has been significant progress in understanding the pathophysiology and treatment of the systemic disease, leading to improved outcomes, but there has been no randomised trial of treatment in the neurological disorder.

show abstract

Section: Aneurysmmentioning

confidence: 99%

“…The neuropathological examination of one fatal case found a lymphocytic infiltration around the vessels and post capillary venules. 136 seizures Epilepsy has a prevalence of 2-5%. 26 37 38 40 44 45 Seizures arise during attacks, are focal more than generalised and become uncommon following treatment.…”

Section: Aneurysmmentioning

confidence: 99%

Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome

Kidd

2023

Pract Neurol

View full text Add to dashboard Cite

show abstract

“…Vascular lesions are commonin manyof the complications of Behcet's syndrome. Most of these lesions are thought to contribute to the occlusive process or to aneurysmformation in large vessels (7). Most cerebrovascular disturbances in Behcet's syndromeare occlusive in nature such as in dural sinus thrombosis (5), while hemorrhage is rare.…”

Section: Introductionmentioning

confidence: 99%

Intracranial Hemorrhage in Neuro-Behcet's Syndrome.

et al. 2002

View full text Add to dashboard Cite

show abstract

Intracranial arterial aneurysm complicating Behçet's disease

İldan

Bağdatoğlu

et al. 1996

Neurosurg. Rev.

View full text Add to dashboard Cite

Behçet's disease, a rare condition in central Europe but more common in Turkey where it was originally described, is characterized clinically by the presence of a diagnostic triad of oral and genital aphthous ulcers, meningitis, and relapsing iridocyclitis. Vascular lesions including arterial and venous occlusions, arterial aneurysms and varices are one of the common complications of Behçet's disease occur most commonly in the abdominal aorta, femoral arteries and pulmonary arteries. There have been only four reports of aneurysms of cerebral arteries in the literature. The authors describe a patient with Behçet's disease who suffered secondary subarachnoid hemorrhage due to a ruptured aneurysm of the anterior communicating artery 3 years after the initial diagnosis. This case report draws further attention to this rare entity in patients with Behçet's disease.

show abstract

Recurrent intracranial haemorrhage in Behcet disease.

Cited by 14 publications

References 7 publications

Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome

Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome

Intracranial Hemorrhage in Neuro-Behcet's Syndrome.

Intracranial arterial aneurysm complicating Behçet's disease

Contact Info

Product

Resources

About