Recurrent inhibition in the cat distal forelimb

Hahne, M.; Illert, M.; Wietelmann, Detlef

doi:10.1016/0006-8993(88)90362-9

Cited by 37 publications

(16 citation statements)

References 9 publications

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“…Second, the anatomical difference between the connections of excitatory and inhibitory INs to the hand motoneurons may account for the facilitatory bias. In cats, a lack of recurrent collateral arbors was reported in the motoneurons innervating digital muscles of the forelimb (Hahne et al, 1988;Hörner et al, 1991) and hindlimb (Cullheim and Kellerth, 1978;McCurdy and Hamm, 1992). These observations suggest that there are fewer recurrent inhibitory neurons for distal muscles.…”

Section: Predominant Facilitations By Spinal Prem-ins To Finger Musclesmentioning

confidence: 93%

Spinal Interneurons Facilitate Coactivation of Hand Muscles during a Precision Grip Task in Monkeys

Takei¹,

Seki²

2010

J. Neurosci.

105

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Section: Predominant Facilitations By Spinal Prem-ins To Finger Musclesmentioning

confidence: 93%

Spinal Interneurons Facilitate Coactivation of Hand Muscles during a Precision Grip Task in Monkeys

Takei¹,

Seki²

2010

J. Neurosci.

105

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“…Recurrent inhibition of motoneurons has been demonstrated throughout the length of the cat spinal cord (Renshaw, 1941;Eccles et al, 1954Eccles et al, , 1961Wilson et al, 1960;Hultbom et al, 1971;Kirkwood et al, 1981;Hahne et al, 1988). Anatomical studies of electrophysiologically identified Renshaw cells, intra- cellularly labeled with dye markers or HRP (Willis and Willis, 1964;Thomas and Wilson, 1965;Jankowska and Lindstriim, 197 1;Walmsley and Tracey, 198 1;Lagerback and Kellerth, 1985b;Fyffe, 1990), have revealed that these cells are almost invariably located in the ventral portion of lamina VII, medial to the main lateral motor nucleus, but can occasionally also be found within the motor nucleus (Fyffe, 1990).…”

Section: Discussionmentioning

confidence: 99%

Distribution of calbindin D28k-like immunoreactivity (LI) in the monkey ventral horn: do Renshaw cells contain calbindin D28k-LI?

et al. 1992

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By use of indirect immunofluorescence and peroxidase-antiperoxidase immunohistochemistry, we show that the monkey (Macaca fascicularis) ventral horn harbors small- to medium-sized neurons in lamina VII as well as a dense network of fibers in laminae IX and VII that contain calbindin D28k (calbindin)-like immunoreactivity. The highest frequency of immunoreactive (IR) cell bodies was found at the levels of the cervical and lumbar intumescences. Furthermore, rostrocaudally oriented calbindin-IR fibers were encountered in the ventral and ventrolateral funiculi throughout the whole length of the cord, with the highest density at cervical and lumbar intumescences. Analysis at the EM level revealed calbindin-IR terminals in contact preferentially with dendrites of variable size and occasionally also large cell bodies, presumably belonging to motoneurons, in the lateral motor nucleus. The location of calbindin-IR neurons, as well as the distribution and ultrastructural characteristics of the calbindin-IR axonal system, makes it highly likely that these neurons are Renshaw cells that mediate recurrent inhibition to motoneurons.

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“…They have also shown the presence of a short latency cutaneous pathway which was discussed in connection with the manipulatory capacity of the paw. A recent study on the distribution of the recurrent inhibition from motor axon collaterals to motoneurones suggests that some motor nuclei to extrinsic paw muscles lack recurrent axon collaterals (Hahne, Illert & Wietelmann, 1988). It is to be expected that a more detailed analysis will reveal further modifications of the spinal functional units in the brachial segments.…”

Section: Adjustment Of Reflex Pathways To Versatile Forelimb Movementsmentioning

confidence: 99%

Pattern of monosynaptic Ia connections in the cat forelimb.

Fritz¹,

Illert²,

Motte³

et al. 1989

The Journal of Physiology

159

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SUMMARY1. In anaesthetized cats intracellular records were obtained from antidromically identified motoneurones. The motor nuclei to the elbow extensor and flexor muscles and to the muscles innervated by the deep radial, ulnar and median nerves were investigated. The maximum Ia EPSPs from electrical stimulation of various peripheral nerves were measured. The characteristic convergence and projection patterns to each motor nucleus were established from pooled data.2. The total aggregates of the I a EPSPs between the different motor nuclei ranged from 3-5 to 11-7 mV. The smallest aggregates were found in the nuclei to the digit muscles. The ratio of the heteronymous versus homonymous EPSP amplitudes varied between 3-9 and 05. A general rule which would govern the distribution of the EPSP aggregates, such as a proximo-distal. gradient, was not observed.3. The Ia connections followed a complex but highly organized pattern. Bidirectional and unidirectional pathways were present. In many cases the convergence pattern of a motor nucleus included muscles acting at different joints. The connections of one nucleus were not necessarily restricted to one side of the limb, but could cross the radio-ulnar plane.4. Muscles with similar actions onto the same joint were interconnected with bidirectional, rather balanced I a pathways. Such relations were also present between close functional synergists and then often extended across several joints. The relations between the anatomical extensors of wrist and digits were graded according to the neighbourhood of these muscles. It is suggested that this reflects the graded mechanical synergism in the wrist action of these muscles.5. A large number of unidirectional or strongly skewed bidirectional Ia pathways project from proximal to distal muscles. It is suggested that they may serve a readjustment of distal joints during changes in the position of proximal ones (e.g. stabilization of the position of the radio-ulnar plane during elbow extension in case of the unidirectional projections onto supinator and abductor pollicis longus motoneurones).

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Recurrent inhibition in the cat distal forelimb

Cited by 37 publications

References 9 publications

Spinal Interneurons Facilitate Coactivation of Hand Muscles during a Precision Grip Task in Monkeys

Spinal Interneurons Facilitate Coactivation of Hand Muscles during a Precision Grip Task in Monkeys

Distribution of calbindin D28k-like immunoreactivity (LI) in the monkey ventral horn: do Renshaw cells contain calbindin D28k-LI?

Pattern of monosynaptic Ia connections in the cat forelimb.

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