Recurrent Idiopathic Intracranial Hypertension

Taktakishvili, Otar; Shah, Vinay; Shahbaz, Reza; Lee, Andrew Go

doi:10.1016/j.ophtha.2007.06.041

Cited by 9 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A retrospective study on recurrence in IIH observed that 44% with recurrence had history of weight gain while 6% were exposed to drugs implicated in IIH (minocycline/tetracycline). 14 Another retrospective study found a statistically significant difference in BMI of patients with recurrence and those without recurrence, concluding that weight gain predisposes a treated patient to recurrence. 15 We sought neurology opinion for all patients with recurrence.…”

Section: Discussionmentioning

confidence: 99%

Change in contrast sensitivity and OCT parameters in idiopathic intracranial hypertension

et al. 2022

View full text Add to dashboard Cite

Background: Deterioration in peripheral contrast sensitivity (CS) can be an indicator to detect progressive deterioration of visual function in patients with idiopathic intracranial hypertension (IIH). Objectives: The aim of this study was to evaluate the changes in central and peripheral CS and optical coherence tomography (OCT) parameters and in patients with IIH. Design and Methods: In this pilot observational study, data of 20 eyes of 10 ‘treatment-naïve’ IIH patients were analyzed. Detailed ocular examination was performed including CS assessment using both Pelli–Robson (PR) test and Spaeth–Richman Contrast Sensitivity Test (SPARCS) along with the OCT for macular and optic nerve head (ONH) parameters. A comparative analysis was done for CS and OCT parameters from baseline to a follow-up visit > 12 months (range: 18–24 months). Results: The study population had a female preponderance (80%, n = 8), and mean age at diagnosis was 31.9 ± 10.3 years. Mean follow-up period was 21.2 months (range: 15–24 months). At presentation, 6/6 visual acuity was noted in 75% eyes ( n = 15) while all eyes had 6/6 vision at the last follow-up. Average PR score increased from 1.96 ± 0.36 to 2.30 at the last visit (Wilcoxon test: V = 0.0, p ⩽ 0.001) while average SPARCS score (total) increased from 71.85 ± 9.10 to 77.55 ± 6.20 (Paired t-test: t = −2.3, p = 0.035). Change in SPARCS score was significant in average total score ( p = 0.035), and quadrant-wise score in superonasal ( p = 0.014), inferonasal ( p = 0.001), and inferotemporal ( p = 0.021) quadrants. Same trend in SPARCS scores was observed when eyes with and without recurrence were analyzed. Statistically significant difference in retinal nerve fiber layer (RNFL) thickness ( p = 0.007) and macular thickness (MT) in nasal quadrant ( p = 0.006) was seen between the eyes with recurrence and without recurrence. Conclusion: Peripheral CS showed significant difference in all eyes over time. It showed significant change in eyes with recurrence, even in the presence of intact visual acuity and preserved central CS. Changes in RNFL thickness and nasal MT could differentiate eyes which developed recurrence from normal eyes.

show abstract

Section: Discussionmentioning

confidence: 99%

Change in contrast sensitivity and OCT parameters in idiopathic intracranial hypertension

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Studies reporting on adults indicate an approximate recurrence rate of 10% 4–6 . In a large retrospective chart review of adults with recurrent PC, Taktakishvili et al 7 . reported on 410 patients with a follow‐up period of greater than 6 months.…”

mentioning

confidence: 99%

“…Our child had two recurrences within 3 years after the initial episode, which suggests that the child was predisposed to the development of PC. Weight disturbances, pregnancy, sleep apnea, hypertension and exposure to tetracycline derivatives were noted as possible comorbidities for recurrence in most studies 4–7 …”

mentioning

confidence: 99%