Recurrent giant retroperitoneal liposarcoma with 10 years follow up. Case report and review of literature

El-Helou, Etienne; Alimoradi, Mersad; Sabra, Hassan; Naccour, Jessica; Haddad, Marwan; Bitar, Henri

doi:10.1016/j.ijscr.2020.09.143

Cited by 3 publications

(2 citation statements)

References 40 publications

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“…A total of 16 original studies with complete and representative data were selected. The clinical data are summarized in Table I (29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44). There were eight males (50%) and eight females (50%), with a median age of 61.5 years (range, 24-73 years).…”

Section: Discussionmentioning

confidence: 99%

Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review

2023

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Retroperitoneal liposarcoma (RPLS) is a rare tumor that occurs in the retroperitoneal region and accounts for ~0.2% of all malignant tumor incidence. The present study describes the treatment of a surviving patient with RPLS that recurred five times in 13 years. This case has a long survival time and numerous relapses, which is a rare occurrence. The 40-year-old female patient was admitted to Shaoxing Second Hospital (Shaoxing, China) with an abdominal mass. Abdominal computed tomography (CT) scan revealed multiple liposarcoma recurrences in the abdominal, pelvic and retroperitoneal areas. As the diagnosis of RPLS was the fifth recurrence, cytoreductive surgery was performed and post-operative pathology suggested mixed liposarcoma. The patient underwent six cycles of doxorubicin and ifosfamide regimen chemotherapy and targeted therapy with anlotinib following surgery; no evidence of disease progression was found on abdominal CT scan during follow-up. The present study also reviewed the literature in terms of the clinical diagnosis, treatment, pathological characteristics and similar cases of liposarcoma with the aim of improving diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review

2023

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“…The absence of tumor (RLS) capsule break-in is a crucial condition for kidney conservation [15] . Avoiding nephrectomy seems also possible when the RLS is widely displacing the kidney [4,16] . In addition to these criteria, the patient's advanced age is another argument for trying to preserve the kidney [11] .…”

Section: Discussionmentioning

confidence: 99%

A Giant retroperitoneal liposarcoma encasing entirely the right kidney: A case report and a review of nephrectomy indications

Harbi

Akrout

Fourati

et al. 2021

Preprint

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Survival of a patient with multiple-recurrent giant retroperitoneal dedifferentiated liposarcoma for 15 years: A case report

Xia

Fang²,

Yuan³

et al. 2022

Front. Surg.

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BackgroundRetroperitoneal liposarcoma (RPLS) is a variety of soft tissue sarcoma that originates from mesenchymal cells. A tumor measuring greater than 30 cm is called a “giant liposarcoma.” A part of the neoplasm tends to grow in size, recur locally, or metastasize distantly. In those with such a condition, long-term survival is uncommon. Therefore, it is necessary to present a uniform and optimized program to improve the prognosis.MethodsBy successfully treating a multiple-recurrent giant retroperitoneal dedifferentiated liposarcoma (RP DDLPS) in July 2010, we hope to devise more comprehensive strategies to improve diagnosis, therapy, and outcome.ResultsIn July 2010, we thoroughly resected a giant multifocal RPLS with a concomitant part of the gastric wall. The histopathological examination revealed a high-grade (grade III) dedifferentiated liposarcoma. The patient was discharged uneventfully on the 15th postoperative day. She relapsed after 16 months and needed another complete excision. After 9 months, she died after the fourth recidive. The patient had experienced four recurrences and underwent operations with 15 years of follow-up.ConclusionsThe above demonstrates that we were able to successfully treat the multirecurrent giant RPLS, despite the patient’s poor medical condition, with meticulous management. Moreover, this indicates that long-term survival could be achieved for high-grade RP DDLPS.

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Recurrent giant retroperitoneal liposarcoma with 10 years follow up. Case report and review of literature

Cited by 3 publications

References 40 publications

Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review

Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review

A Giant retroperitoneal liposarcoma encasing entirely the right kidney: A case report and a review of nephrectomy indications

Survival of a patient with multiple-recurrent giant retroperitoneal dedifferentiated liposarcoma for 15 years: A case report

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