Recurrent Fibromyoma of the Vagina

Ingemanson, Carl-Axel; J, Alfredsson

doi:10.3109/00016347009157250

Cited by 8 publications

(1 citation statement)

References 15 publications

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“…Various benign and malignant, epithelial and mesenchymal, tumors occur within the vaginal wall, and smooth muscle tumors represent the most common mesenchymal tumors occurring in adults. The first case of vaginal leiomyoma was reported in 1733 [1], and since then more than 250 cases have appeared in the literature [2][3][4]. They occur in patients from puberty to 71 years of age [4] but are most common between the ages of 38 and 48 years [5].…”

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Vaginal Leiomyoma with Heterologous Paragangliomatous Elements

Naidoo

2000

Int J Surg Pathol

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A vaginal leiomyoma with heterologous paragangliomatous elements is reported. The patient was a 62-year-old woman who presented with uterovaginal prolapse and an asymptomatic vaginal mass that had been present for many years. Histology of the excised mass showed a leiomyoma in a submucosal location, with irregularly shaped islands of chief cells scattered throughout the lesion. These cells were arranged in nests and were surrounded by S100 protein-positive sustentacular cells. The chief cells showed immunoreactivity with chromogranin, synaptophysin, and neuron-specific enolase. Although various heterologous elements are commonly encountered within uterine leiomyomata, such elements have not been described within vaginal leiomyomata. Furthermore, the occurrence of paragangliomatous tissue within leiomyomata has not been reported to date. Int J Surg Pathol 8(4):359-365, 2000

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confidence: 99%