Recurrent cornual pregnancy, successfully treated with methotrexate, following a ruptured pregnancy in the contralateral cornu

Fabre-Gray, Anna; Read, M. D.; Wardle, Peter G.; James, Mark

doi:10.3109/01443615.2013.819844

Cited by 7 publications

(7 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This interstitial portion of the fallopian tube is highly vascular; rupture results in excessive intraperitoneal hemorrhage. Although these pregnancies represent approximately 2 to 4 % of all ectopic pregnancies, maternal mortality is high (2 % of cases) due to the risk of uterine rupture and subsequent hemorrhagic shock [ 1 – 4 ]. The routine use of early ultrasonography has enabled the development of minimally invasive surgical techniques before serious complications occur.…”

Section: Introductionmentioning

confidence: 99%

Considerations for management of interstitial ectopic pregnancies: two case reports

Grindler

Tocce

et al. 2016

J Med Case Reports

View full text Add to dashboard Cite

BackgroundConventional treatment of interstitial pregnancies includes systemic methotrexate, direct methotrexate injection, wedge resection, or hysterectomy. We present two cases of interstitial pregnancies that were successfully managed by different minimally invasive surgical techniques. We also report the novel use of hysteroscopic urologic stone retrieval forceps in the transvaginal removal of persistent products of conception after systemic methotrexate for an interstitial pregnancy.Case presentationCase 1 was a 28-year-old gravida 1 white woman at 8 weeks gestation; she was diagnosed with a left interstitial pregnancy. After laparoscopic confirmation of the interstitial pregnancy, successful ultrasound-guided suction dilation and curettage was performed. Case 2 was a 33-year-old gravida 3 para 1021 (one term pregnancy, no preterm pregnancies, one ectopic pregnancy and one spontaneous miscarriage, and one living child) Hispanic woman with persistent products of conception after systemic methotrexate for a left interstitial pregnancy. She underwent hysteroscopic-guided removal of the persistent products of conception, which was possible due to novel use of urologic stone retrieval forceps.ConclusionsSuccessful minimally invasive treatment of interstitial pregnancies may be possible in certain cases. Collaboration between different specialties continues to be important for improving minimally invasive options.

show abstract

Section: Introductionmentioning

confidence: 99%

Considerations for management of interstitial ectopic pregnancies: two case reports

Grindler

Tocce

et al. 2016

J Med Case Reports

View full text Add to dashboard Cite

show abstract

“…Interstitial portion of tube with surrounding myometrium is often distensible, vascular and pregnancy at this site may get unnoticed for long. There can be life threatening haemorrhage if cornual pregnancy ruptures before diagnosis [4][5][6] . Clinicians should be aware of the diagnostic and therapeutic challenges and keep high index of suspicion for such cases.…”

Section: Discussionmentioning

confidence: 99%

A case study of ruptured cornual ectopic with successful outcome in subsequent pregnancy

2021

IJCR

View full text Add to dashboard Cite

Cornual pregnancy is a fearful condition with dreadful complications. Due to rarity and late presentation, it poses diagnostic and therapeutic challenges. There is no consensus on treatment strategies till date and risk of rupture after repair in subsequent pregnancy always remains a major concern. We hereby discuss a case of 27 year female who presented with ruptured cornual ectopic pregnancy, underwent cornual wedge resection with repair and had subsequent pregnancy with a successful outcome.

show abstract

“…The mortality rate in cornual pregnancy is 2% to 2.5%, and a history of ipsilataral salpengectomy, a previous ectopic pregnancy, and pelvic inflammatory disease are risk factors. 11 …”

Section: Discussionmentioning

confidence: 99%

“…In addition, the probability of uterine rupture was reported to be 10% to 15% after uterine surgery, regardless of reconstructive surgery. 11 If reconstructive surgery is performed before pregnancy, the rupture risk decreases to 1%. That is a good pre-pregnancy policy for a consecutive pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Treatment of unruptured cornual pregnancies by local injections of methotrexate or potassium chloride under transvaginal ultrasonographic guidance

et al. 2018

View full text Add to dashboard Cite

Objective:To demonstrate the outcome of intralesional management and show the safety of local treatment of cornual pregnancy.Methods:Eight patients were treated with local methotrexate or potassium chloride injection. All patients underwent transvaginal ultrasound examination and were diagnosed by the criteria defined by Timor-Tritsch. In the case of fetal heart beat observation, potassium chloride was injected; and in the case of no heart beat detection, methotrexate was used. A follicle aspiration needle was inserted directly into the gestational sac under transvaginal guidance.Results:Although it has been considered to be a risk factor, none of the patients in our study had previous ectopic pregnancy, history of infertility / in vitro fertilization, or cornual pregnancy. One of the patients had a medical history of abortion. In four cases, methotrexate was injected, and three patients received potassium chloride as a local treatment. None of the patients had any complication in the peri- or postoperative period.Conclusion:Using a local approach, the treatment agent can reach the area of the cornual pregnancy in high concentrations. Based on this case series, a local approach seems to be an effective and fertility-sparing method for treating unruptured cornual pregnancies.

show abstract

Recurrent cornual pregnancy, successfully treated with methotrexate, following a ruptured pregnancy in the contralateral cornu

Cited by 7 publications

References 4 publications

Considerations for management of interstitial ectopic pregnancies: two case reports

Considerations for management of interstitial ectopic pregnancies: two case reports

A case study of ruptured cornual ectopic with successful outcome in subsequent pregnancy

Treatment of unruptured cornual pregnancies by local injections of methotrexate or potassium chloride under transvaginal ultrasonographic guidance

Contact Info

Product

Resources

About