Recurrent Corneal Erosion Syndrome: A Study of 364 Episodes

Abstract

The purpose of the study was to investigate the management of recurrent corneal erosion syndrome (RES). A retrospective case series design was employed in which all RES cases presenting to the Duke University Eye Center from 1995 to 2002 were included. In total, 364 episodes of RES occurred in 261 patients during the study period. Of this 61% of patients were female (P < .001), average age was 46.0 years, and etiologies included trauma (51.3%), anterior basement membrane dystrophy (29.1%), other etiologies (10.3%) and unknown (9.2%). Treatments included conservative therapy (83.2%), anterior stromal puncture (ASP)(12.6%) and phototherapeutic keratectomy (PTK)(4.1%). Recurrence by treatment was 31.0% for conservative therapy, 23.9% for ASP and 26.7% for PTK. Subjects treated with ASP and PTK had failed prior treatment efforts. Conclusions include that RES was commonly associated with trauma and the female gender, and that one-third of conservatively treated episodes and one-quarter of surgically treated episodes (ASP or PTK) recurred.

Long-Term Clinical Outcome of Low-Temperature Plasma Ablation Treatment for Recurrent Corneal Erosions

“…Preoperative eye pain was assessed using the VAS scale: a score of 3 in two patients (5.7%), 5 in five patients (14.3%), 6 in nine patients (25.7%), 7 in three patients (8.6%), 8 in nine patients (25.7%), 9 in one patient (2.9%), 10 in twelve patients (34.3%). Additionally, the mean eye pain score is 7.7 ± 2.4 [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ]. All patients had histories of eye pain, watering, and increased sensitivity to light on waking as well as typical RCE manifestations under the slit lamp examination.…”

“…The length of these episodes can vary, ranging from minutes to hours to days, and they might occur frequently or merge into a continuous period of suffering [ 1 ]. According to the literature, trauma and epithelial basement membrane degradation (EBMD) are the two most typical causes [ 3 , 4 , 5 , 6 , 7 ]. Fingernail injury was shown to be the most prevalent mechanism in a subgroup study of the different causes of RCEs, followed by exposure to vegetable debris [ 5 ].…”

Intense Pulsed Light Combined With Meibomian Gland Massage for Recurrent Corneal Erosion: a Review of Clinical Effectiveness

“…The main goal of the treatment is to relieve symptoms and reduce recurrence. Nevertheless, no treatment can prevent recurrence by now, and data shows that all treatments' recurrence rate was still above 20 percent [16][17][18] .…”

Recurrent corneal erosion: modern view of the problem

“…По данным различных исследований, методика стромальной пункции эффективна в 50-80% случаев [58]. Она имеет низкую стоимость, относительно безопасна, проста, выполняется в амбулаторных условиях под щелевой лампой.…”