Recurrent atypical fibroxanthoma of the limbus

Abstract

We report an unusual presentation of recurrent atypical fibroxanthoma of the limbus. Clinical and histological appearances, as well as management are discussed and the current literature is reviewed.

Atypical Fibroxanthoma of the Bulbar Conjunctiva

“…6 The sole case of AFX reported in the palpebral conjunctiva was in a 94-yearold woman. 8 Previous conjunctival AFX cases have been either spindle-cell predominant 7,9 or more pleomorphic with numerous histocyte-like (epithelioid) cells and multinucleated giant cells, as in our patient. 6,8 Treatment of conjunctival AFX relies on complete excision, 7 similar to therapy for skin AFX.…”

“…1 Incomplete excision may result in local tumor recurrence. 1,7 Too few cases of conjunctival AFX have been reported to know whether there is any metastatic potential, but this seems extremely unlikely based on the biological behavior of skin AFX.…”

“…1,2 AFX has been reported only rarely in the eyelid 3-5 or conjunctiva. [6][7][8][9] Three of the conjunctival AFX cases involved the bulbar conjunctiva at the limbus 6,7,9 and one was in the palpebral conjunctiva. 8 Previous cases of AFX of the bulbar conjunctiva were in a 5 and 1/2-year-old boy with xeroderma pigmentosum, 5 and men aged 59 8 and 81.…”

“…1,2 Only rarely has AFX been reported in the eyelid [3][4][5] or conjunctiva. [6][7][8][9] We describe an AFX arising on the bulbar conjunctiva near the corneal limbus.…”

Atypical Fibroxanthoma of the Bulbar Conjunctiva: A Unique Case Describing the Pathology, Clinical Presentation, and Management

“…Data on recurrence in ocular lesions is limited, however. There are a few case reports of recurrent atypical fibroxanthoma of the eyelid and limbus [14,15]. Follow-up is recommended annually for monitoring of recurrence.…”