Recurrent Angina following Coronary Artery Bypass Surgery Solutions In The Current Era

Mathew, Samuel K.; Gopal, Rakesh

doi:10.1016/s0976-0016(12)60034-9

Cited by 1 publication

(1 citation statement)

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“…Atherosclerotic plaques can cause narrowing or blockage of coronary arteries and reducing blood flow and oxygen to the heart muscle (Cesar et al, 2014). Coronary artery bypass graft (CABG) surgery is one of the major treatment strategies for severe CAD (Yang et al, 2015); it is a surgical procedure to relieve angina (Samuel and Gopal, 2004). The aims of CABG surgery are to reduce previous symptoms of patients with coronary disease such as discomfort from chest pain (Yang et al, 2015), reduce the risk of heart attack, increase patient’s chance of living longer (Harris et al, 2013) and improve quality of life (QoL) (Järvinen et al, 2003; Panagopoulou et al, 2006; Kaur et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Neurocognitive Rehabilitation After Coronary Artery Bypass Graft Surgery in Improving Quality of Life: An Interventional Trial

et al. 2019

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Introduction Cognitive deficits are frequent after coronary artery bypass graft (CABG) surgery and consequently could lead to a decrease in quality of life. This is the first study that has been conducted with the aim of examining the efficacy of a computerized cognitive rehabilitation therapy (CCRT) in improving quality of life in patients after CABG surgery. Methods In this study, an interventional trial with pre-, post-, and follow-up assessments in active (CCRT), active control and control groups was conducted. Seventy-five patients after CABG surgery were selected and assigned to the groups ( n = 25 for each group). CCRT consists of four modules of attention, working memory, response inhibition and processing speed training with graded schedule in 20-min sessions three times per week within 8 weeks. Cognitive functions (attention and working memory) were assessed by the tests of continuous performance, Flanker, useful field of view and digit span at three time points: pre- and post-intervention (T0 and T1) and 6-month follow-up (T2). Quality of life was assessed by the SF-36 questionnaire at the same time points. The CCRT group received the cognitive rehabilitation for 2 months, active control group received a sham version of CCRT in an equal time duration and control group did not receive any cognitive intervention. Results Repeated measures analysis of variance (ANOVA) revealed a time by group interaction on cognitive functions, with CCRT producing a significant improvement at T1 ( p < 0.01) and these improvements were maintained at T2. Moreover, in CCRT and active control groups, quality of life (QoL) improved at T1 and these improvements remained stable throughout follow-up (T2). However, improvement of QoL in CCRT group was greater than improvement of QoL in the other two groups at T1. Pearson’s correlation analysis shows a positive correlation between QoL improvement and sustained attention and working memory enhancement ( p < 0.05). Conclusion Cognitive rehabilitation can lead to a significant improvement in the cognitive functions that have been trained in patients receiving CABG. Interestingly enough, cognitive rehabilitation can also improve quality of life in patients after CABG surgery and this improvement is maintained for at least 6 months.

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