Recurrent and resistant duodenal ulcer revealing Thromboangiitis obliterans

Abstract

Thromboangiitis obliterans or Leo Burger’s disease is a rare systemic vasculitis in young and typically heavy smoker male, whose diagnosis is a real challenge for the clinician. Digestive manifestations are rare and unusual in this disease and the inaugural intestinal involvement is extremely found. We report an original case of relapsing and resistant duodenal ulcer revealing a Leo Buerger’s disease in a 42 year old man.

Intestinal manifestation of Buerger’s disease in a middle-age female with subsequent transverse colon perforation: A case report and review of literature

“…The rare cases of TAO with involvement of the GI tract have manifested in the small intestine, 19–21 and cases of TAO causing ischemic colitis with perforation are scarce, 22 and the majority of confirmed cases of visceral intestinal TAO occur in men. 13,19,21–32,34–52…”

“…The rare cases of TAO with involvement of the GI tract have manifested in the small intestine, [19][20][21] and cases of TAO causing ischemic colitis with perforation are scarce, 22 and the majority of confirmed cases of visceral intestinal TAO occur in men. 13,19,[21][22][23][24][25][26][27][28][29][30][31][32][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52] Our patient is unique with features of TAO. While only the upper extremities were reported to be affected and we do not have the full diagnostic workup to support the provided history of TAO, given the histology and fulfillment of Olin's criteria, we can attribute the patient's diagnosis to Buerger's disease after excluding other causes of her vasculitis.…”

“…The rare cases of TAO with involvement of the GI tract have manifested in the small intestine, 19–21 and cases of TAO causing ischemic colitis with perforation are scarce. 22 The majority of confirmed cases of visceral intestinal TAO occur in men 13,19,21–52 (Table 1). We present a unique case of a 45-year-old female patient with a history of TAO who presented with ischemic colitis.…”