Recurrent and Injurious Falls in the Year Following Hip Fracture: A Prospective Study of Incidence and Risk Factors From the Sarcopenia and Hip Fracture Study

Lloyd, Bradley D.; Williamson, Dominique A.; Singh, Nalin; Hansen, Ross; Diamond, Terrence; Finnegan, Terence P; Allen, Barry J.; Grady, Jodie N.; Stavrinos, Theodora M.; Smith, Emma; Diwan, Ashish D.; Singh, Maria A. Fiatarone

doi:10.1093/gerona/glp003

Cited by 159 publications

(113 citation statements)

References 49 publications

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“…In almost 900 older adults, men but not women with sarcopenic obesity had increased odds of reporting a past-year fall (OR: 3.34, 95% CI 1.37-8.26) (5). A study including 193 communitydwelling older adults examined the year after hip fracture did not report an association for sarcopenic obesity with falls outcomes (27). This evidence suggests that inconsistent associations exist between sarcopenic obesity and falls in older adults and similarly inconsistent associations with physical performance outcomes previously are likely due in part to heterogeneous definitions (28).…”

Section: Discussionmentioning

confidence: 99%

Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults

Scott

Sanders

Aitken

et al. 2014

Obesity

105

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Objectives: To determine whether obesity concurrent with sarcopenia (low muscle mass) or dynapenia (low muscle strength) is associated with increased falls risk in middle-aged and older adults. Methods: 5-year prospective cohort study including 674 community-dwelling volunteers (mean 6 SD age 61.4 6 7.0 years; 48% female). Sarcopenia and dynapenia were defined as lowest sex-specific tertiles for dual-energy X-ray (DXA)-assessed appendicular lean mass (adjusted for height and fat mass) or lowerlimb strength, respectively. Obesity was defined as the highest tertiles of DXA-assessed total or trunk fat mass. Change in falls risk was calculated using the Physiological Profile Assessment (z-scores: 0-1 5 mild increased risk; 1-2 5 moderate increased risk; >2 5 marked increased risk). Results: Multivariable linear regression analyses revealed mild but significantly increased falls risk scores for dynapenic obesity (change in mean z-score compared to non-dynapenic, non-obese group: 0.33, 95% CI 0.06-0.59 [men] and 0.46,) and dynapenia (0.25, 95% CI 0.05-0.46 [women only]). Conclusions: Dynapenic obesity, but not sarcopenic obesity, is predictive of increased falls risk score in middle-aged and older adults.s In clinical settings, muscle function assessments may be useful for predicting falls risk in obese patients.

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Section: Discussionmentioning

confidence: 99%

Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults

Scott

Sanders

Aitken

et al. 2014

Obesity

105

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“…7,8 It has been estimated that 55.6% of hip fracture patients had at least one fall within 12 months, 11.8% sustained a fall-related fracture and 5% sustained a fall-related hip fracture. 9 Mortality during the first year after fracture ranges from 8.4% to 36%. 4 …”

Section: Introductionmentioning

confidence: 99%

Models of care for the delivery of secondary fracture prevention after hip fracture: a health service cost, clinical outcomes and cost-effectiveness study within a region of England

Judge

Javaid

Leal

et al. 2016

Health Serv Deliv Res

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms VOLUME 4 ISSUE 28 SEPTEMBER 2016 ISSN 2050 DOI 10.3310/hsdr04280 HEALTH SERVICES AND DELIVERY RESEARCHModels of care for the delivery of secondary fracture prevention after hip fracture: a health service cost, clinical outcomes and cost-effectiveness study within a region of England Andrew Judge, M Kassim Javaid, José Leal, Samuel Hawley, Sarah Drew, Sally Sheard, Daniel Prieto-Alhambra, Rachael Gooberman-Hill, Janet Lippett, Andrew Farmer, Nigel Arden, Alastair Gray, Michael Goldacre, Antonella Delmestri and Cyrus Cooper Models of care for the delivery of secondary fracture prevention after hip fracture: a health service cost, clinical outcomes and cost-effectiveness study within a region of England Declared competing interests of authors: Daniel Prieto-Alhambra has received unrestricted research and educational grants from Amgen and Bioibérica S.A. Nigel Arden reports personal fees from Merck Sharp & Dohme (MSD), grants and personal fees from Roche, personal fees from Smith and Nephew, personal fees from Q-Med, personal fees from Nicox, personal fees from Flexion, personal fees from Bioibérica and personal fees from Servier. Cyrus Cooper has received consultancy fees, lecture fees and honoraria from Amgen, GlaxoSmithKline, Alliance for Better Bone Health, Eli Lilly, Pfizer, Novartis, MSD, Servier, Medtronic and Roche. M Kassim Javaid has in the last 5 years received honoraria for travel expenses, speaker fees and/or advisory committees from Lilly UK, Amgen, Servier, MSD, Medtronic, Internis, Consilient Health and Jarrow Formulas. He also serves on the Scientific Committee of the National Osteoporosis Society and International Osteoporosis Foundation. Andrew Judge has received consultancy fees, lecture fees and honoraria from Servier, UK Renal Registry, Oxford Craniofacial Unit, IDIAP Jordi Gol and Freshfields Bruckhaus Deringer, is a member of the Data Safety and Monitoring Board (which involved receipt of fees) from Anthera Pharmaceuticals, Inc., and received consortium research grants from Roche.Published September 2016 DOI: 10.3310/hsdr04280 This report should be referenced as follows:Judge A, Javaid MK, Leal J, Hawley S, Drew S, Sheard S, et al. Models of care for the delivery of secondary fracture prevention after hip fracture: a health service cost, clinical outcomes and cost-effectiveness study within a region of England. Health Serv Deliv Res 2016;4(28). Health Services and Delivery ResearchISSN 2050-4349 (Print) ISSN 2050-4357 (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full HS&DR archive is freely available to view online at www.journalslibrary.nihr.ac.uk/hsdr. Print-on-demand copies can be purchased from the repor...

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“…I en studie fant man at 56 % av pasientene med hoftebrudd opplevde et nytt fall i løpet av det første året. 12 % av disse fallene resulterte i et brudd og 5 % i et nytt hoftebrudd (10). Årsakene til fall er mange og sammensatte, og utreding av falltendens hos pasienter med mange kroniske sykdommer og uklar fallårsak er en typisk geriatrisk oppgave (11).…”

Section: Forebygging Av Nye Bruddunclassified

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Johnsen¹,

Watne²,

Frihagen³

et al. 2015

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Recurrent and Injurious Falls in the Year Following Hip Fracture: A Prospective Study of Incidence and Risk Factors From the Sarcopenia and Hip Fracture Study

Cited by 159 publications

References 49 publications

Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults

Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults

Models of care for the delivery of secondary fracture prevention after hip fracture: a health service cost, clinical outcomes and cost-effectiveness study within a region of England

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