Recurrent adamantinoma in the thoracolumbar spine successfully treated by three-level total en bloc spondylectomy by a single posterior approach

Duan, Ping‐Guo; Li, Ruoyu; Jiang, Yun-qi; Wang, Hui-Ren; Zhao, Xiaogang; Li, Xilei; Wang, Yichao; Dong, Jian

doi:10.1007/s00586-014-3625-z

Cited by 13 publications

(9 citation statements)

References 22 publications

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“…Primary adamantinoma of the spine is also rare, with six cases described in the literature. Whether primary or metastatic, growth within the spine has been described as slow and with a propensity for local recurrence despite treatment [5] . In a case report by Dini et al, a primary adamantinoma of the spine was described which involved multiple levels of the lower cervical/upper thoracic spine, including the lateral masses and transverse processes [6] .…”

Section: Discussionmentioning

confidence: 99%

Recurrent adamantinoma metastatic to the spine: Clinical and imaging considerations

Marteslo

Bourekas

Boulter

et al. 2021

Radiology Case Reports

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Metastatic adamantinoma involving the spine is an extremely rare occurrence. In this case report, we present a patient with recurrent adamantinoma of the tibia which was found to have metastasized to the spine. The metastatic involvement was diagnosed pathologically, status post CT guided percutaneous core needle biopsy, performed after the patient returned with concerning symptoms and imaging findings suggestive of metastasis. The patient was ultimately treated surgically with vertebrectomy and reconstruction. A thoughtful review of this disease process is explored, emphasizing the pathology, imaging characteristics, and pertinent differential diagnostic considerations. While uncommon, knowledge of this rare disease process and its presentation can improve future patient diagnosis and outcomes.

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Section: Discussionmentioning

confidence: 99%

Recurrent adamantinoma metastatic to the spine: Clinical and imaging considerations

Marteslo

Bourekas

Boulter

et al. 2021

Radiology Case Reports

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“…Corpectomy is generally accepted as an effective surgical procedure for spinal cancer metastasis, infection, deformity, and traumatic injuries [1, 2]. However, restoration of the spinal column during surgery remains a technical challenge in clinical practice [3, 4]. To create a biological environment for fusion, rigid stabilization with an ideal vertebral body graft is highly recommended, and a number of interbody graft types have been constructed including allografts, cement, metal, and synthetic materials [5–9].…”

Section: Introductionmentioning

confidence: 99%

Biomechanical analysis of a novel height-adjustable nano-hydroxyapatite/polyamide-66 vertebral body: a finite element study

et al. 2019

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BackgroundTo compare the biomechanical properties of a novel height-adjustable nano-hydroxyapatite/polyamide-66 vertebral body (HAVB) with the titanium mesh cage (TMC) and artificial vertebral body (AVB), and evaluate its biomechanical efficacy in spinal stability reconstruction.MethodsA 3D nonliner FE model of the intact L1-sacrum was established and validated. Three FE models which instrumented HAVB, TMC, and AVB were constructed for surgical simulation. A pure moment of 7.5 Nm and a 400-N preload were applied to the three FE models in 3D motion. The peak von Mises stress upon each prosthesis and the interfaced endplate was recorded for analysis. In addition, the overall and intersegmental range of motion (ROM) of each model was investigated to assess the efficacy of each model in spinal stability reconstruction.ResultsAVB had the greatest stress concentration compared with TMC and HAVB in all motions (25.6–101.8 times of HAVB, 0.8–8.1 times of TMC). The peak stress on HAVB was 3.1–10.3% of TMC and 1.6–3.9% of AVB. The maximum stress values on L2 caudal and L4 cranial endplates are different between the three FE models: 0.9–1.9, 1.3–12.1, and 31.3–117.9 times of the intact model on L2 caudal endplates and 0.9–3.5, 7.2–31.5, and 10.3–56.4 times of the intact model on L4 cranial endplates in HAVB, TMC, and AVB, respectively, while the overall and segmental ROM reduction was similar between the three models, with AVB providing a relatively higher ROM reduction in all loading conditions (88.1–84.7% of intact model for overall ROM and 69.5–82.1% for L1/2, 87.0–91.7% for L2/4, and 71.1–87.2% for L4/5, respectively).ConclusionsHAVB had similar biomechanical efficacy in spinal stability reconstruction as compared with TMC and AVB. The material used and the anatomic design of HAVB can help avoid stress concentration and the stress shielding effect, thus greatly reducing the implant-associated complications. HAVB exhibited some advantageous biomechanical properties over TMC and AVB and may prove to be a potentially viable option for spinal stability reconstruction. Further in vivo and vitro studies are still required to validate our findings and conclusions.

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“…Adamantinoma commonly affects the tibia, particularly the anterior diaphysis and metaphysis, accounting for 85%-90% of the cases ( 7 ). Primary or metastatic spinal adamantinoma of bone are rarer, and only four cases have been documented in the previous literature ( 8 – 11 ). Our center describes two cases of metastatic spinal adamantinoma with more aggressive biological behaviors and uncommon radiographic appearances.…”

Section: Introductionmentioning

confidence: 99%

Rapidly Progressive Classic Adamantinoma of the Spine: Case Report and Literature Review

Lou

Liu

et al. 2022

Front. Oncol.

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Adamantinoma is a locally aggressive or malignant tumor, accounting for <0.5% of all primary bone tumors. The tumor usually progresses slowly, with a relatively promising prognosis. Primary or metastatic spinal adamantinoma of bone are rarer. Only four cases have been documented till date. We present two cases of aggressive spinal adamantinoma whose microphotography and radiographic appearance were unusual, with extensive involvement of multiple segments and rapid progression. Case 1 was a 36-year-old woman, presenting with back pain, progressive numbness and motor weakness, who was diagnosed with metastatic adamantinoma in the T2, T7, L2, and L4. She underwent spondylectomy three times to resect these lesions, respectively. Case 2 was a 68-year-old male with complaints of severe left back pain. MRI revealed destructive changes in T1-T4. He underwent posterior decompression (T1-T3), partial vertebrectomy (T2), fixation and fusion (C5-C7, T4-T6). The pathology of two patients was metastatic spinal adamantinoma, whose primary lesions were from tibia and femoral adamantinoma, respectively. Rapid squamous progression was observed in specimens of T2 and T7 lesions of Case 1 in two months. Twenty-five months after surgery, Case 1 developed paralysis, but she refused to receive further examination and treatment. Two months after surgery, Case 2 presented with an upper back pain again. The MRI revealed an increase in osseous destruction and paravertebral mass size. He was administered radiotherapy, with his upper back pain partially relieved. The biological behavior of classic adamantinoma is highly unpredictable, often exhibiting more aggressive behavior upon recurrence or metastasis. The pathological diagnosis of adamantinoma should be confirmed by preoperative biopsy. En bloc resection with a wide margin is the preferred treatment for primary spinal adamantinoma. Radiation therapy can partially relieve the pain.

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Recurrent adamantinoma in the thoracolumbar spine successfully treated by three-level total en bloc spondylectomy by a single posterior approach

Abstract: This is the first case involving multilevel thoracolumbar spinal adamantinoma with repeated recurrence to be successfully treated by three-level TES by a single posterior approach.

Cited by 13 publications

References 22 publications

Recurrent adamantinoma metastatic to the spine: Clinical and imaging considerations

Recurrent adamantinoma metastatic to the spine: Clinical and imaging considerations

Biomechanical analysis of a novel height-adjustable nano-hydroxyapatite/polyamide-66 vertebral body: a finite element study

Rapidly Progressive Classic Adamantinoma of the Spine: Case Report and Literature Review

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