Recurrence rate of sphenoid sinusitis after medical therapy

Catheter- and Antibiotic-Related Complications of Ambulatory Intravenous Antibiotic Therapy for Chronic Refractory Rhinosinusitis

“…In chronic recalcitrant rhinosinusitis, multiple or prolonged courses of oral antibiotics have had variable success with significant recurrence rates. 8 Thus, recent attention has been focused toward other methods of antibiotic delivery that may result in higher antibiotic concentrations in the nasal and paranasal tissues.…”