Recurrence rate of oral squamous cell papilloma after excision with surgical scalpel or laser therapy: A retrospective cohort study

Abstract

Background The aim was to describe the recurrence rates of Oral Squamous Cell Papilloma (OSCP) following surgical treatment with surgical scalpel and two different lasers (CO2 or Er,Cr;YSGG) and to determine the clinical and histopathologic features of these lesions. Material and Methods A retrospective cohort study covering a period of 12 years (1997-2009) that included patients diagnosed of OSCP treated with surgical excision was performed. Data was processed using SPSS 22.0 (SPPS Inc. Chicago, USA) and a descriptive and bivariate analysis were conducted. Results A total of 37 histopathologically confirmed OSCP in 36 patients, 19 women (52.7%) and 17 men (47.2%) with an average age of 33.4 years (14-86 years) were included. Twenty-two cases were treated by excision with surgical scalpel excision, 11 with CO2 laser and 3 with Er,Cr:YSGG laser. The mean age was 35.4 years (14-86 years) and the distribution by gender was 19 women (52.7%) and 17 men (47.2%). The most common locations were the palate in 14 cases (37.8%), followed by the tongue in 11 cases (29.7%) and gingiva with 5 cases (13.5%). The average size of the lesions was 4.25 mm in diameter, with a mean evolution time of 5.9 months. The recurrence rate was slightly higher with the CO2 laser (14.3 %) in comparison with the conventional scalpel (10%). No recurrences for Er,Cr:YSGG were found. Conclusions No differences for recurrence rates for OSCP between groups were found. The recurrence rate is low, happening usually before 15 months of follow-up. OSCPs are lesions usually appearing in patients between 30 and 50 years of both genders and located predominantly on the palate, tongue and gingiva. Key words: Oral squamous cell papilloma, squamous cell papilloma, CO2 laser, recurrence.

Prevention of Recurrence of Oral HPV-Related Lesions: Systematic Review of the Literature and Meta-Analysis

“…Their reported difference in recurrence rate was 10% for cold-blade treated lesions than 18% for laser-treated lesions. However, this difference was not statistically significant [13].…”

“…The recurrence rate of lasertreated lesions is 5.98%, while the recurrence rate of cold-blade excision is 4.07%. The most extensive studies on cold-blade excision are the 2015 study by Frigerio et al and the 2019 study by Toledano-Sarrabona et al [13,25]. Frigerio [17,26,27].…”

Unusual Manifestation of Benign Squamous Papilloma of the Uvula: A Case Report and Review of Literature

“…The treatment of choice is complete surgical excision including the base of the lesion and a small marginal area to prevent recurrence. The use of laser treatments has also been proposed to eliminate oral squamous cell papilloma, rather than the surgical scalpel [9].…”

Malignant transformation of oral squamous cell papilloma: a case report

“…According to the classification of the World Health Organization (WHO), oral squamous cell papilloma is a benign hyperplastic exophytic localized proliferation with a verrucous or cauliflower-like morphology, which its base may be sessile or pedunculated [ 9 ]. It was reported to have two types: isolated-solitary in adults and multiple-recurring in children.…”

“…It was reported to have two types: isolated-solitary in adults and multiple-recurring in children. The color of the lesion varies depending on the level of keratinization and vascularization [ 9 ]. Oral squamous papilloma is regarded as an innocuous lesion that is neither transmissible nor threatening [ 10 ].…”