Recurrence of Sudden Infant Death Syndrome

Bacon, Christopher M.

doi:10.1542/peds.2008-1924

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…Siblings of SIDS cases have a statistically higher risk of SIDS due to the persistence of genetic and environmental risk factors [5,33]. Increased risk in siblings is difficult to quantify [5,6] but has been estimated at 5.8 [14].…”

Section: Role Of Lqts In Unexplained Sidsmentioning

confidence: 99%

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Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives

Baruteau

Joomye

et al. 2009

Eur J Pediatr

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Section: Role Of Lqts In Unexplained Sidsmentioning

confidence: 99%

“…It is of paramount importance that the first death be thoroughly investigated, particularly for conditions that could recur, such as inborn error of metabolism [26,58,59], covert homicide, or primary electrical disease like LQTS [5].…”

Section: Role Of Lqts In Unexplained Sidsmentioning

confidence: 99%

Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives

Baruteau

Joomye

et al. 2009

Eur J Pediatr

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Unintentional asphyxia, SIDS, and medically explained deaths: a descriptive study of outcomes of child death review (CDR) investigations following sudden unexpected death in infancy

Garstang

Ellis

Griffiths

et al. 2016

Forensic Sci Med Pathol

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BackgroundA comprehensive Child Death Review (CDR) program was introduced in England and Wales in 2008 but as yet data have only been analysed at a local level, limiting the learning from deaths. The aim of this study is to describe the profile of causes and risk factors for Sudden Unexpected Death in Infancy (SUDI) as determined by the new CDR program. MethodsThis was a descriptive outcome study using data from Child Death Overview Panel (CDOP) Form C for SUDI cases dying during 2010-2 in the West Midlands region of England. The main outcome measures were: cause of death, risk factors and potential preventability of death, and determination of deaths probably due to unintentional asphyxia. ResultsData were obtained for 65/70 (93%) SUDI cases. 20/65 (31%) deaths were initially categorised as due to medical causes; 21/65 (32%) as SIDS, and 24/65 (37%) as undetermined. Reanalysis suggested that 2/21 SIDS and 7/24 undetermined deaths were probably due to unintentional asphyxia, with 6 of these involving co-sleeping and excessive parental alcohol consumption. Deaths classified as 'undetermined' had significantly higher total family and environmental risk factor scores (mean 2.6, 95% CI 2.0-3.3) compared to those classified as SIDS (mean 1.6, 95% CI 1.2-1.9), or medical causes for death (mean 1.1, 95% CI 0.8-1.3). 9/20 (47%) of medical deaths, 19/21 (90%) SIDS and 23/24 (96%) undetermined deaths were considered to be potentially preventable. There were inadequacies in medical provision identified in 5/20 (25%) of medically explained deaths. ConclusionsThe CDR program results in detailed information about risk factors for SUDI cases but failed to recognise deaths probably due to unintentional asphyxia. The misclassification of probable unintentional asphyxial deaths and SIDS as 'undetermined deaths' is likely to limit learning from these deaths and inhibit prevention strategies. Many SUDI occurred in families with mental illness, substance misuse and chaotic lifestyles and most in unsafe sleep-environments. This knowledge could be used to better target safe sleep advice for vulnerable families and prevent SUDI in the future. Key Words Key pointsThe CDR program provides valuable information on the profile of causes and risk factors for SUDI but is currently not recognising deaths from unintentional asphyxia and often not classifying unexplained infant deaths as SIDS.Most SUDI still occur in hazardous sleep environments despite public health campaigns.Poor parenting, particularly the combination of excess parental alcohol consumption and cosleeping, was a factor in many unexplained SUDI deaths.Research is needed to help target safe-sleep information better at high risk families.Difficulties with health care service provision may have contributed to some medically explained deaths.

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How common is repeat sudden infant death syndrome?

Bacon¹,

Hall

Stephenson

et al. 2008

Archives of Disease in Childhood

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Recurrence of sudden infant death syndrome (SIDS) is rare but may give rise to confusion and controversy because of the differential diagnoses of familial disease or covert homicide. We examine eight studies of recurrent SIDS published in English since 1970. These studies reported relative risks of recurrence, as compared with the population or with controls, ranging from 1.7 to 10.1. We assess the validity of the studies by three main criteria: accuracy of ascertainment, adequacy of investigation and matching of controls. We found that all the studies failed to meet these criteria, and we think that their flaws would have resulted mainly in overestimation of recurrence risk. We conclude that, although an increase in risk is probable on theoretical grounds, this risk cannot be quantified from the available evidence. We suggest that professionals should be cautious in their pronouncements on the chances of recurrence, and that parents who have lost a baby to SIDS can, with the exception of particularly vulnerable families, be reassured that the risk of recurrence is small.

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Recurrence of Sudden Infant Death Syndrome

Cited by 4 publications

References 4 publications

Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives

Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives

Unintentional asphyxia, SIDS, and medically explained deaths: a descriptive study of outcomes of child death review (CDR) investigations following sudden unexpected death in infancy

How common is repeat sudden infant death syndrome?

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