Recurrence of Kikuchi's lymphadenitis after 12 years

Blewitt, R W; Kumar, Santosh; Abraham, Jebin

doi:10.1136/jcp.53.2.157

Cited by 38 publications

(17 citation statements)

References 6 publications

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“…In agreement with these data, Al-Nazer and colleagues did not observe any new flareup of the disease in a small group of patients who were followed up to 12 years after the diagnosis [3]. As far as we know, there are only two other reports of patients who had a flare-up of the disease more than 10 years, respectively 12 and 19 years, since the first episode [4,5]. In those two patients and in our case as well, no other systemic disease, such as cancer, lymphoma, or systemic lupus erythematosus (SLE), developed over such a prolonged follow-up period.…”

Section: Discussionsupporting

confidence: 65%

Kikuchi Fujimoto lymphadenitis: Case report and literature review

et al. 2003

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We describe a young woman with two severe episodes of Kikuchi Fujimoto disease occurring 16 years apart. Both episodes were proven by biopsy, and on the second occasion the patient remained dependent on high-dose prednisone for more than 6 months in order to control inflammation and achieve a reduction in cervical lymph node size. The second lymph node biopsy showed leukocytoclastic vasculitis in addition to the typical features of Kikuchi Fujimoto disease, but, even though the clinical interpretation of this finding was unclear, we documented no clinical or laboratory evidence of the development of other serious systemic disease over 20 years of follow-up. Kikuchi Fujimoto disease is considered a disorder with a self-limited course and a favorable outcome. However, on the basis of our experience with this patient and data from peerreviewed literature, we suggest that this generally accepted postulate should be revised.

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Section: Discussionsupporting

confidence: 65%

Kikuchi Fujimoto lymphadenitis: Case report and literature review

et al. 2003

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“…The disease was first described in 1972 by two Japanese scientists Kikuchi and Fujimoto [1][2][3]. KFD is more prevalent in the Asian nations than in the western world.…”

Section: Introductionmentioning

confidence: 99%

The Role of PET/CT in the Diagnosis of Kikuchi-Fujimoto Disease: A Case Series and Review of the Literature

Mghanga¹,

Bakari²,

Mayala³

2017

J Mol Imaging Dynam

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Introduction: Kikuchi-Fujimoto disease (KFD), also known as Kikuchi's disease or histiocytic necrotizing lymphadenitis, is a self-limiting case of non-cancerous lymphadenopathy. Although previous reports have demonstrated its physical findings and traditional imaging characteristics, few studies mentioned the application of 18 fluorodeoxyglucose positron emission tomography-computed tomography ( 18 F-FDG PET/CT) imaging in the diagnosis and follow-up of this disease. Here, we present three cases of KFD, describe the findings from PET/CT images and review relevant literature to improve the diagnosis of this rare disease.

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“…Laboratory abnormalities may include leukopenia, an elevated serum transaminase level, and an elevated serum LDHlevel which was noted in this patient (6,9). The relapse or recurrence rate is low, and has been reported to be approximately 3% (10). In the present patient, we could not clearly determine whetheror not the numerousprevious episodes of fever and arthralgia, except for the most recent episode, were due to HNL.…”

Section: Discussionmentioning

confidence: 51%

Immediate Remission Obtained by Minocycline in a Patient with Histiocytic Necrotizing Lymphadenitis.

et al. 2001

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A 29-year-old man was admitted because of fever, arthralgia and swelling of the cervical lymph nodes. A diagnosis of histiocytic necrotizing lymphadenitis (HNL) was madebased on the findings of a lymph node biopsy. At first, piperacillin sodium (PIPC) was started, but a spiking fever persisted. Wetherefore changed the PIPC treatment to minocycline. On the following day, his clinical and laboratory findings were dramatically improved. After administering minocycline for 10 days, the HNLsymptoms completely disappeared. He has been in good health for 3 years since undergoing treatment. This case strongly indicates that minocycline-sensitive microorganism(s) maybe related, at least in part, to the etiology of HNL.

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Recurrence of Kikuchi's lymphadenitis after 12 years

Cited by 38 publications

References 6 publications

Kikuchi Fujimoto lymphadenitis: Case report and literature review

Kikuchi Fujimoto lymphadenitis: Case report and literature review

The Role of PET/CT in the Diagnosis of Kikuchi-Fujimoto Disease: A Case Series and Review of the Literature

Immediate Remission Obtained by Minocycline in a Patient with Histiocytic Necrotizing Lymphadenitis.

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