Recurrence of Breast Carcinoma Following Immediate Reconstruction

Local recurrence following mastectomy and autologous breast reconstruction: incidence, risk factors, and management

“…The outcome strongly confirmed the primary importance of physical examination in the surveillance of LR for this specific target population of patients undergoing post-MST ABR, even though mammography, ultrasound, and magnetic resonance imaging may have advantages over physical examination under some circumstances 19–21. On the other hand, it implied that the presence of flaps didn’t delay the detection of recurrent lesions, which was also consistent with conclusions in previous studies 6,14…”

“…However, a small but significant number of patients develop local, regional, or distant recurrence after BR. Therefore, some literature had discussed about locoregional recurrence and distant recurrence after BR 6–8. However, few studies reported about local recurrence (LR) after ABR 9.…”

Late results of skin-sparing mastectomy followed by immediate breast reconstruction

“…Indications for SSM and IBR have continued to broaden and recent studies report the technique being used even for advanced stages of breast carcinoma15–17. Other studies have analysed recurrence rates after SSM and IBR, although generally with short follow‐up10, 11, 16–31. The present 10‐year series of 207 women with a mean follow‐up of 70 months provides a reasonably good image of the perioperative complications and recurrence rates for different tumour stages.…”

Ten-year follow-up of skin-sparing mastectomy followed by immediate breast reconstruction

“…Determination of the true rates of locoregional and distant recurrence is essential to allow reliable assessment of the oncological safety of SSM. In published studies with longer than 60 months' follow‐up, local recurrence rates of 0–11·1 per cent and locoregional recurrence rates of 1–12·9 per cent have been reported ( Table S1 , supporting information)1, 7–9, 17, 23, 25, 32, 43, 45–52. These rates are somewhat higher than those obtained with shorter follow‐up.…”

“…The local recurrence rate mirrors only the quality of the oncosurgical technique of SSM, whereas regional recurrence provides information about the quality of axillary surgery, which is especially important in patients with moderate‐ or high‐risk breast cancer. Almost half of the long‐term oncological follow‐up studies did not clearly report on local and locoregional recurrence rates7, 23, 25, 43, 45, 46, 49, 51, and most did not disclose tumour size or stage either1, 7, 23, 25, 32, 43, 45–47, 49–52. Moreover, the data on high‐risk patients are difficult to interpret, given that in six studies the subgroups were small and too highly selected for useful interpretation25, 43, 46–49.…”