Recurrence after conventional versus daylight photodynamic therapy in children effected by multiple facial flat warts

Borgia, Francesco; Macca, Laura; Giuffrida, Roberta; Coppola, Marialorena; Princiotta, Rosaria; Vaccaro, Mario; Guarneri, Fabrizio; Cannavò, Serafinella Patrizia

doi:10.1016/j.pdpdt.2021.102579

Cited by 2 publications

(3 citation statements)

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“…None of non-responders at 24 weeks achieved improvement at 1-year follow-up. No long-term side effects were reported in both groups ( Borgia et al, 2021 ).…”

Section: Pdt and Pediatric Infectious Skin Diseasesmentioning

confidence: 89%

Photodynamic therapy in pediatric age: Current applications and future trends

et al. 2022

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Photodynamic therapy (PDT) is a photochemotherapy based on local application of a photosensitive compound and subsequent exposure to a light source of adequate wavelength. It is a non-invasive therapeutic procedure widely used in oncodermatology for treatment of numerous skin cancers, but in the last years its use has been gradually extended to an increasing list of skin diseases of both infectious and inflammatory nature. Although PDT is proven as a safe and effective therapeutic option in adults, its use is not well standardized in the pediatric population. In this review, we will focus on clinical applications, mechanisms of action, protocols, and adverse events in children and adolescents. Most of pediatric experiences concerned treatment of skin cancers in Gorlin syndrome and xeroderma pigmentosum, acne vulgaris, and viral warts, but other applications emerged, such as cutaneous lymphoma and pseudo-lymphomas, necrobiosis lipoidica, hidradenitis suppurativa, dissecting cellulitis, leishmaniasis, angiofibromas, verrucous epidermal nevus, and linear porokeratosis. In these pediatric diseases, PDT appeared as an effective therapeutic alternative. The results on vitiligo were limited and not fully encouraging. Although highly versatile, PDT is not a therapy for all skin diseases, and a deeper knowledge of its mechanisms of action is required to better define its spectrum of action and safety in pediatric patients.

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“…None of non-responders at 24 weeks achieved improvement at 1-year follow-up. No long-term side effects were reported in both groups ( Borgia et al, 2021 ).…”

Section: Pdt and Pediatric Infectious Skin Diseasesmentioning

confidence: 89%

Photodynamic therapy in pediatric age: Current applications and future trends

et al. 2022

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“…6 In this study, we confirm the high efficacy and safety of C-PDT with 5-ALA in the pediatric setting. 4,7,8 An otherwise healthy 5-year-old female was brought to our attention by her parents for a 30-months history of multiple skin-colored, verrucous papules in the perineal area (Figure 1A). She had been previously visited by many physicians (both pediatricians and dermatologists) with a diagnosis of GWs, and treated with imiquimod 5% cream and cryotherapy, which were ineffective, and poor tolerated by the patient.…”

mentioning

confidence: 99%

“…Many variables influence the treatment eligibility, such as the size, quantity, and location of the warts. 4 Invasive treatments (surgical excision, cryotherapy, carbon dioxide laser, and electrocoagulation) are painful…”

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confidence: 99%

Photodynamic therapy for pediatric genital warts: A case report

Macca

Pomi

Custurone

et al. 2022

Dermatologic Therapy

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Genital warts (GWs) are the most common sexually transmitted infections (STIs), caused by the human papillomavirus. 1 The most common way of infection in adults is sexual, but transmission in pediatric populations remains controversial. 2 The increasing prevalence of GWs in children, ranged from 0% to 80%, 3 has renewed the interest in understanding the social and legal impact in cases of sexual abuse. In addition to concerns regarding the potential abuse, treatment for GWs in pediatric populations also present a unique challenge. Many variables influence the treatment eligibility, such as the size, quantity, and location of the warts. 4 Invasive treatments (surgical excision, cryotherapy, carbon dioxide laser, and electrocoagulation) are painful

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Recurrence after conventional versus daylight photodynamic therapy in children effected by multiple facial flat warts

Cited by 2 publications

References 5 publications

Photodynamic therapy in pediatric age: Current applications and future trends

Photodynamic therapy in pediatric age: Current applications and future trends

Photodynamic therapy for pediatric genital warts: A case report

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