Recuperación de la Morfología y Fisiología Maxilo Mandibular: Biomateriales en Regeneración Ósea

Venegas, Gonzalo; Fernández, Ramón Fuentes; Cantoni, Héctor Álvarez; Echeverría, Eduardo Borie

doi:10.4067/s0717-95022008000400013

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…The repair and regeneration of lost or damaged alveolar bone presents significant problems in dentistry. Previous studies have indicated that the chances of success are increased when the induction of regeneration is induced with autologous compounds, since the use of autologous compounds is associated with an improved prognosis and the absence of the biocompatibility problems that may occur with synthetic graft materials or grafts of a heterologous nature ( 1 , 2 ).…”

Section: Introductionmentioning

confidence: 99%

Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

Rivera

Monsalve

Salas

et al. 2013

Experimental and Therapeutic Medicine

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Platelet preparations promote bone regeneration by inducing cell migration, proliferation and differentiation in the area of the injury, which are essential processes for regeneration. In addition, several studies have indicated that simvastatin (SIMV), widely used for the treatment of hypercholesterolemia, stimulates osteogenesis. The objective of this study was to evaluate the effects of treatment with either platelet-rich plasma (PRP) or plasma rich in growth factors (PRGF) in combination with SIMV in the regeneration and repair of alveolar bone. The jaws of Sprague Dawley rats (n=18) were subjected to rotary instrument-induced bone damage (BD). Animals were divided into six groups: BD/H2O (n=3), distilled water without the drug and alveolar bone damage; BD/H2O/PRP (n=3), BD and PRP; BD/H2O/PRGF (n=3), BD and PRGF; BD/SIMV (n=3), BD and water with SIMV; BD/SIMV/PRP (n=3), BD, PRP and SIMV; and BD/SIMV/PRGF (n=3), BD, PRGF and SIMV. Conventional histological analysis (hematoxylin and eosin staining) revealed that the BD/SIMV group showed indicators for mature bone tissue, while the BD/SIMV/PRP and BD/SIMV/PRGF groups showed the coexistence of indicators for mature and immature bone tissue, with no statistical differences between the platelet preparations. Simvastatin did not improve the effect of platelet-rich plasma and plasma rich in growth factors. It was not possible to determine which platelet preparation produced superior effects.

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Section: Introductionmentioning

confidence: 99%

Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

Rivera

Monsalve

Salas

et al. 2013

Experimental and Therapeutic Medicine

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Preserving Dental Alveolus Using Allograft

Pinto

2018

Int J Med Surg Sci

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The loss of alveolar bone volume is a physiological consequence of tooth loss, which if not done carefully preserved and becomes a significant functional and aesthetic risk for the installation of osseointegrated dental implants. The dimensional differences of the alveolar ridge can be attenuated with different graft materials and surgical procedures. The presentation of this case illustrates one of the various surgical techniques to reduce bone resorption and maintain the volume of tissue to be rehabilitated in a more predictable manner and reducing problems in the future, thus increasing the chances of successful rehabilitation osseointegrated dental implant.

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Recuperación de la Morfología y Fisiología Maxilo Mandibular: Biomateriales en Regeneración Ósea

Cited by 2 publications

References 14 publications

Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

Preserving Dental Alveolus Using Allograft

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