Rectal ulcer in a hemodialysis patient receiving Kayexalate<sup>®</sup>

Collot, Julia; Salaouatchi, Mohamed Tayeb; Rickaert, Fabienne; Floriani, Albino; Buysschaert, Benoît; Mesquita, Maria; Godon, Eric

doi:10.1002/ccr3.4043

Cited by 4 publications

(1 citation statement)

References 28 publications

(49 reference statements)

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“…The distinctive diamond-shaped crystals of SPS exhibit a characteristic fish scale appearance, thus serving as a histological hallmark when discerned on the intestinal surface epithelium. 6 , 7 …”

Section: Discussionmentioning

confidence: 99%

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Jaan,

Sarfraz,

Malik

et al. 2023

Journal of Community Hospital Internal Medicine Perspectives

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Sodium polystyrene sulphonate (SPS), employed in the management of severe hyperkalemia, is typically combined with sodium sorbitol to avert potential intestinal obstruction. Nonetheless, the administration of Kayexalate, even in the presence of minimal sorbitol, can lead to the grave complication of colonic necrosis. We present a case of Kayexalate-mediated colonic necrosis, highlighting the vital necessity of acknowledging the inherent risks associated with its usage in spite of its efficacy in potassium reduction. In light of these potential risks, it is incumbent upon physicians to exercise caution, and contemplate the use of alternative pharmacological agents that effectively eliminate excess potassium, whilst minimizing associated adverse effects.

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Section: Discussionmentioning

confidence: 99%

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Jaan,

Sarfraz,

Malik

et al. 2023

Journal of Community Hospital Internal Medicine Perspectives

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Sodium-polystyrene-sulfonate

2021

Reactions Weekly

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Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration

Thorpe,

Vinagre,

Santos

et al. 2024

Journal of Surgical Case Reports

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Cation exchange resins are commonly used as treatment for hyperkalaemia in patients with chronic renal disease. There is a relation between cation exchange resins and the development of gastrointestinal adverse effects. A case of an intestinal obstruction at the terminal ileum is presented that underwent an ileocolic resection because of a critical stenosis of the intestine. The pathologist revealed abundant inflammatory cells together with deposits of calcium polystyrene crystals responsible of the intestinal obstruction. A rare cause of intestinal obstruction to bear in mind in chronically medicated patients with cation exchange resins.

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Rectal ulcer in a hemodialysis patient receiving Kayexalate^®

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 4 publications

References 28 publications

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Sodium-polystyrene-sulfonate

Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration

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Rectal ulcer in a hemodialysis patient receiving Kayexalate®

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 4 publications

References 28 publications

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Sodium-polystyrene-sulfonate

Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration

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Product

Resources

About

Rectal ulcer in a hemodialysis patient receiving Kayexalate^®