Rectal <i>Trichomonas vaginalis</i> infection in South African men who have sex with men

Hoffman, Charlotte M; Fritz, Lise; Radebe, Oscar; Dubbink, Jan Henk; McIntyre, James; Kock, Marleen M.; Peters, Remco P. H.

doi:10.1177/0956462418788418

Cited by 15 publications

(14 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Infections with T. vaginalis among MSM were not uncommon, although less frequent than N. gonorrhoeae / C. trachomatis and not significantly higher than in other multipartner men. Other research has suggested that T. vaginalis may circulate within MSM networks and not result from concurrent sexual contact with women [27]. Our multivariable model suggests that transmission of T. vaginalis (and M. genitalium) is less specific to MSM, and less dependent on typical STI determinants such as the number of sexual partners.…”

Section: Yearly Incidence During Follow-upmentioning

confidence: 56%

The Swiss STAR trial – an evaluation of target groups for sexually transmitted infection screening in the sub-sample of men

Schmidt

Rasi

Esson³

et al. 2020

Swiss Med Wkly

View full text Add to dashboard Cite

OBJECTIVES: In Switzerland, universal health insurance does not cover any routine testing for sexually transmitted infections (STIs), not even in individuals at high risk, and extra-genital swabbing is not standard of care. We determined the prevalence and incidence of human immunodeficiency virus (HIV), viral hepatitis and non-viral STIs in a multicentre prospective observational cohort of multi-partner men who have sex with men (MSM) and other men.MATERIALS AND METHODS: Between January 2016 and June 2017, we offered free STI testing to all men with multiple sexual partners (three or more in the previous 12 months), with follow-up examinations every 6 months. We used multiplex polymerase chain-reaction testing (for Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Mycoplasma genitalium) on pooled swabs (pharynx, urethra/vagina, anus), and antibody tests for HIV and Treponema pallidum at every visit, and for hepatitis B/C at baseline. RESULTS: We screened 779 multi-partner MSM and 92 other men. Previously undiagnosed HIV was found in 0.5% vs 0.0%, respectively and T. pallidum antibodies in 15.3% vs 1.1%. STIs requiring antibiotic treatment comprised: active syphilis 1.7% vs 0.0%; N. gonorrhoeae 10.3% vs 0.0%; C. trachomatis 8.7% vs 1.1%. One in four MSM versus 1 in 100 other multi-partner men had any of these three STIs at baseline. 10.4% vs 1.3% had a history of hepatitis B, 31.9% vs 47.3% had no immunity (HBs-AB <10 IU/l). Ten MSM had HCV antibodies (1.4%), with 8 out of the 10 being MSM with HIV; HCV seroprevalence was 0.3% among HIV-negative MSM. In MSM, incidence of the three bacterial STIs was 25.5 per year over 333 person years of follow-up, HIV incidence was 0.3%. Non-condom-use (in the last 3 months) for anal/vaginal sex was not associated with STIs. Independent risk factors were sex with men (adjusted odds ratio [aOR] 16.4) and the number of sexual partners (aOR 2.3 for >20). CONCLUSION: Among MSM, but not among other multipartner men, STIs, mostly asymptomatic, are common. Given the high risk of onward transmission, low-cost or free routine screening of multi-partner MSM is a public health priority.

show abstract

Section: Yearly Incidence During Follow-upmentioning

confidence: 56%

The Swiss STAR trial – an evaluation of target groups for sexually transmitted infection screening in the sub-sample of men

Schmidt

Rasi

Esson³

et al. 2020

Swiss Med Wkly

View full text Add to dashboard Cite

show abstract

“…16 Prior studies have validated NAAT for NG, CT, and TV in urethral samples 17 18 as well as NG and CT in anal samples. 19 20 However, few studies have reported on anal TV, 21-24 and we found no studies of anal TV in transgender women. Reported prevalence of anal TV among MSM have ranged from <1% 20 24 to 9%.…”

Section: Discussionmentioning

confidence: 82%

“…Reported prevalence of anal TV among MSM have ranged from <1% 20 24 to 9%. 21 Similarly, prevalence of anal TV among cisgender women has ranged from 1.2% 22 to 6.3%. 23 Our finding of positive anal TV results ranging from 4.8% to 14.3% across study visits is consistent with the studies in cisgender populations.…”

Section: Discussionmentioning

confidence: 99%

Characterizing HIV and STIs among Transgender Female Sex Workers: A Longitudinal Analysis

Poteat

White

Footer

et al. 2020

Preprint

View full text Add to dashboard Cite

Objectives: Though highly vulnerable to HIV and STIs, transgender female sex workers (TFSW) are understudied in the U.S. HIV and STI response. This study examined the correlates of laboratory-confirmed STIs among a cohort of 62 TFSW followed over the course of one year and explored associations between specimen site and self-reported engagement in insertive and receptive anal intercourse. Methods: Participants completed an interviewer-administered computer assisted personal interview at baseline, 3-, 6-, 9-, and 12-month visits where self-administered anal swabs and urine samples for gonorrhea, chlamydia, and trichomonas were also collected. HIV testing was conducted at baseline, 6-, and 12-month visits. Results: Baseline HIV prevalence was 40.3% with no HIV seroconversions over follow-up. Baseline prevalence of gonorrhea, chlamydia, and trichomonas was 9.7%, 17.7%, and 14.5%, respectively. In the multivariable regression modeling, recent arrest was significantly associated with testing positive for any STI (aRR 1.77; 95% CI: 1.10-2.84). Insertive anal sex with clients was associated with increased risk of testing positive for an STI via urine specimen (RR 3.48; 95% CI: 1.14-10.62), while receptive anal sex was not significantly associated with specimen site. Conclusion: Our findings confirm a high prevalence of STIs among TFSW and highlight the importance of addressing structural drivers such as criminal justice involvement as well as the need to ensure screening for STIs at all anatomical sites regardless of self-reported sites of potential exposure. More research is needed to better understand HIV and STI vulnerabilities and appropriate interventions for TFSW in the U.S.

show abstract

“…Furthermore, high rates of various sexually transmitted infections (STI) among MSM have been reported in various countries in SSA. These include: Chlamydia trachomatis (CT) in Tanzania−7.5% (10) and Kenya−26% (13); Mycoplasma genitalium (MG) in Nigeria−36.8% (14); Neisseria gonorrhoae (NG) in Tanzania−14.4% (10) and Kenya−26% (13); Treponema pallidum (TP) in Malawi−12.3% (6) and Uganda−9% (11); and Trichomonas vaginalis (TV) in South Africa−9% (15).…”

Section: Introductionmentioning

confidence: 99%

“…Globally, the HIV epidemic remains poorly defined among young men who have sex with men (YMSM) aged [15][16][17][18][19][20][21][22][23][24] Abbreviations: AIDS, acquired immunodeficiency syndrome; CARTA, consortium for advanced research training in Africa; CBO, community-based organization; CT, Chlamydia trachomatis; HCP, healthcare providers; HIV, human immunodeficiency virus; IBBA, integrated bio-behavioral assessment; IQR, inter-quartile range; MG, Mycoplasma genitalium; MSM, men who have sex with men; NASCOP, national AIDS and STI control program; NG, Neisseria gonorrhoeae; NGO, non-governmental organization; PHDA, partners in health and development in Africa; PI, principal investigator; PSE, population size estimation; RDS, respondent-driven sampling; REDCap, research electronic data capture; SSA, Sub-Saharan Africa; STATA, software for statistics and data science; STI, sexually transmitted infections; TP, Treponema pallidum; TSMSM, tertiary student men who have sex with men; TV, Trichomonas vaginalis; UAI, unprotected anal intercourse; WHO, World Health Organization; YMSM, young men who have sex with men.…”

Section: Introductionmentioning

confidence: 99%

Project BESPOKE (Integrated Bio-Behavioral Assessment of HIV and STI Among Young Tertiary Student Men Who Have Sex With Men in Nairobi, Kenya): A Respondent-Driven Sampling Survey Protocol

Mwaniki

Mugo

Palanee‐Phillips

2021

Front. Public Health

View full text Add to dashboard Cite

Introduction: Globally, men who have sex with men (MSM) are a key population for the human immunodeficiency virus (HIV) epidemic. Among MSM, young men who have sex with men (YMSM) are disproportionately affected by HIV and other sexually transmitted infections (STI). However, there is a dearth of research and interventions targeting HIV/STI prevention among YMSM. In Kenya, there is paucity of knowledge on the burden of HIV/STI and related factors among YMSM, including tertiary student men who have sex with men (TSMSM). The barriers TSMSM experience in accessing and utilizing health services in their learning institutions have seldom been explored. In the context of healthcare providers (HCP) working in tertiary institutions, little is known about their knowledge, attitudes, and practices toward providing services to TSMSM.Methods: The aims of the study are to: estimate prevalence and correlates of HIV/STI among TSMSM; estimate population size of TSMSM; explore experiences of TSMSM with access and utilization of health services; and assess HCP knowledge of, attitudes toward, and practices in provision of services to TSMSM. A mixed-methods approach will be used in three phases: Phase I—formative qualitative research will be conducted to understand TSMSM social networks, select “seeds”, and explore strategies for implementing a respondent-driven sampling (RDS) survey. Interviews will be conducted with at least three staff who work in community based/non-governmental organizations (CBO/NGO) that serve MSM and at least 10 TSMSM. Phase II—an integrated bio-behavioral assessment (IBBA) will be conducted, where 200 TSMSM recruited by RDS will be offered HIV/STI testing, complete a behavioral survey, and provide information for population size estimation (PSE). Phase III—in-depth interviews will be held with 20 TSMSM selected from 200 TSMSM in phase II, to explore their experiences with access and utilization of healthcare services. Focus group discussions (FGD) will be conducted with HCP working in tertiary institutions to assess their knowledge of, attitudes toward, and practices in providing services to TSMSM. Data collection started in September 2020 and is expected to end by September 2021.Discussion: Findings from this study will be useful in informing HIV/STI prevention programming for TSMSM, by policy makers such the Kenyan ministries of health and education, tertiary education institutions, service providers, advocacy groups, and other interested stakeholders.

show abstract

Rectal Trichomonas vaginalis infection in South African men who have sex with men

Cited by 15 publications

References 18 publications

The Swiss STAR trial – an evaluation of target groups for sexually transmitted infection screening in the sub-sample of men

The Swiss STAR trial – an evaluation of target groups for sexually transmitted infection screening in the sub-sample of men

Characterizing HIV and STIs among Transgender Female Sex Workers: A Longitudinal Analysis

Project BESPOKE (Integrated Bio-Behavioral Assessment of HIV and STI Among Young Tertiary Student Men Who Have Sex With Men in Nairobi, Kenya): A Respondent-Driven Sampling Survey Protocol

Contact Info

Product

Resources

About