Rectal Cancer: Primary Staging and Assessment After Chemoradiotherapy

Evans, Jessica; Patel, Uday; Brown, Gina

doi:10.1016/j.semradonc.2011.02.002

Cited by 71 publications

(55 citation statements)

References 68 publications

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“…It is limited in highly stenosing tumors and in tumors situated in the upper third of the rectum. 86 The mesorectal fascia for the most part is not visualized with this technique.…”

Section: Colorectal Cancermentioning

confidence: 99%

Potential Role of Positron Emission Tomography/Magnetic Resonance Imaging in Gastrointestinal and Abdominal Malignancies: Preliminary Experience

Teixera

Kohan

Paspulati

et al. 2014

Seminars in Roentgenology

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“…It is limited in highly stenosing tumors and in tumors situated in the upper third of the rectum. 86 The mesorectal fascia for the most part is not visualized with this technique.…”

Section: Colorectal Cancermentioning

confidence: 99%

Potential Role of Positron Emission Tomography/Magnetic Resonance Imaging in Gastrointestinal and Abdominal Malignancies: Preliminary Experience

Teixera

Kohan

Paspulati

et al. 2014

Seminars in Roentgenology

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“…Damit können diejenigen Patienten identifiziert werden, bei denen trotz TME-Chirurgie und kompletter Tumorentfernung ein hohes Risiko für lokoregionäre und/oder systemische Rezidive besteht und bei denen daher eine neoadjuvante Therapie indiziert erscheint [1].…”

Section: Therapieansätzeunclassified

“…Die Untersuchung ist vielerorts verfügbar, kostengünstiger als die MRT und weitestgehend untersucherunabhängig. Aktuell liegt die Hauptindikation der MDCT nach neoadjuvanter Therapie in der Verlaufsbeurteilung von Fernmetastasen, wofür sie gut geeignet ist [1].…”

Section: Introductionunclassified

Rektumkarzinom – Lokales Staging und Bildgebung unter neoadjuvanter Therapie

Karpitschka

2012

Radiologe

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“…The aim of preoperative staging is to accurately and Diffusion Weighted Sequence reproducibly differentiate between good and poor prognosis tumors. Prognostic stratification includes assessment of depth of spread, nodal status, extramural vascular invasion (EMVi), CRM and peritoneal invasion [8].…”

Section: Introductionmentioning

confidence: 99%

Rectal Carcinoma, Recent Staging Strategy by MRI Using Diffusion Weighted Sequence

Mousa¹,

Abdella²

2017

IJMI

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Abstract:Objective: MRI is currently the imaging modality of choice for the detection, characterization, and staging of rectal cancer. A variety of examinations have been used for preoperative staging of rectal cancer, including digital rectal examination, endorectal (endoscopic) ultrasound, CT, and MRI. Endoscopic ultrasound is the imaging modality of choice for small and small superficial tumors. MRI is superior to CT for assessing invasion to adjacent organs and structures, especially low tumors that carry a high risk of recurrence. Background: Colorectal cancer (CRC) is the third most common cancer in both sexes combined worldwide, after prostate and breast cancer with an incidence of 40 in 100,000. Rectal carcinoma accounts for more than one-third of colorectal tumors and is associated with significant morbidity and mortality. Currently, MRI using diffusion weighted sequence is the most sensitive and specific modality in staging rectal cancer as it is able to depict the mesorectal fascia and its relation to the tumor margins precisely. Methods: This study included 50 patients, (32 male and 18 female) previously diagnosed as cancer rectum based on proctoscope and histopathological biopsy. The age range of the patients was from 18 years to 78 years. All patients will be subjected to the following: detailed history, clinical examination, proctoscopic assessment and histopathological data. All patients underwent MRI of the pelvis specifically cancer rectum protocol. Results: The most frequently encountered clinical presentation among cancer rectum patients was bleeding per rectum (14), constipation (26), incidentally discovered liver metastasis (6) and intestinal obstruction (4). MRI evaluation of T staging in correlation to the histopathological examination showed sensitivity (80%), specificity (93%), accuracy (94%). Lymph node (LN) metastatic spread was evaluated by MRI and showed sensitivity (87%), specificity (92%), accuracy (92.6%), PPV (84.8%) and NPV (96.7%). Regarding circumferential resection margin (CRM) MRI assessment revealed; sensitivity (96%), specificity (94%), accuracy (96%), PPV (95%) and NPV (94.3%). Conclusions: MRI is an accurate and sensitive imaging method delineating tumoral margins, mesorectal fascia involvement, lymph nodes, and distant metastasis. MRI can accurately delineate the mesorectal fascia involvement, which is one of the main decision points in planning treatment.

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Rectal Cancer: Primary Staging and Assessment After Chemoradiotherapy

Cited by 71 publications

References 68 publications

Potential Role of Positron Emission Tomography/Magnetic Resonance Imaging in Gastrointestinal and Abdominal Malignancies: Preliminary Experience

Potential Role of Positron Emission Tomography/Magnetic Resonance Imaging in Gastrointestinal and Abdominal Malignancies: Preliminary Experience

Rektumkarzinom – Lokales Staging und Bildgebung unter neoadjuvanter Therapie

Rectal Carcinoma, Recent Staging Strategy by MRI Using Diffusion Weighted Sequence

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