Recruiting young women to a trial of chlamydia screening

Atherton, Helen; Banks, Debbie; Harbit, Ruth; Oakeshott, Pippa

doi:10.1258/095646206780070974

Cited by 3 publications

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“…Strategies such as prompting participants to confirm their contact details prior to sending out follow up have been demonstrated to increase the return of postal surveys,[18] Other studies also suggest that having a dedicated research team and being flexible and creative help to increase recruitment rates [19,20] and interestingly, whilst gifts and money provide incentives to be involved, young women are only likely to be part of a study if they feel it is an altruistic thing to do[20,21]. …”

Section: Discussionmentioning

confidence: 99%

Maximising retention in a longitudinal study of genital Chlamydia trachomatis among young women in Australia

et al. 2011

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BackgroundCohort studies are an important study design however they are difficult to implement, often suffer from poor retention, low participation and bias. The aims of this paper are to describe the methods used to recruit and retain young women in a longitudinal study and to explore factors associated with loss to follow up.MethodsThe Chlamydia Incidence and Re-infection Rates Study (CIRIS) was a longitudinal study of Australian women aged 16 to 25 years recruited from primary health care clinics. They were followed up via the post at three-monthly intervals and required to return questionnaires and self collected vaginal swabs for chlamydia testing. The protocol was designed to maximise retention in the study and included using recruiting staff independent of the clinic staff, recruiting in private, regular communication with study staff, making the follow up as straightforward as possible and providing incentives and small gifts to engender good will.ResultsThe study recruited 66% of eligible women. Despite the nature of the study (sexual health) and the mobility of the women (35% moved address at least once), 79% of the women completed the final stage of the study after 12 months. Loss to follow up bias was associated with lower education level [adjusted hazard ratio (AHR): 0.7 (95% Confidence Interval (CI): 0.5, 1.0)], recruitment from a sexual health centre as opposed to a general practice clinic [AHR: 1.6 (95% CI: 1.0, 2.7)] and previously testing positive for chlamydia [AHR: 0.8 (95% CI: 0.5, 1.0)]. No other factors such as age, numbers of sexual partners were associated with loss to follow up.ConclusionsThe methods used were considered effective for recruiting and retaining women in the study. Further research is needed to improve participation from less well-educated women.

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Section: Discussionmentioning

confidence: 99%

Maximising retention in a longitudinal study of genital Chlamydia trachomatis among young women in Australia

et al. 2011

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“…Thirdly we offered small incentives in the form of lollipops and coloured pens. Increasingly participants are expecting a reward for helping with research [ 4 ] and these incentives were well received. We also appealed to participants' possible altruistic side by emphasising the important contribution participants might make to research into women's health by giving just 10 minutes of their time.…”

Section: Discussionmentioning

confidence: 99%

Recruitment of young women to a trial of chlamydia screening – as easy as it sounds?

Atherton

Banks

Harbit

et al. 2007

Trials

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Background: Recruiting to trials is complex and difficult. The Prevention of Pelvic Infection (POPI) trial aims to see if screening women for chlamydia and treating those found to be infected reduces the incidence of pelvic inflammatory disease in the following twelve months. It focuses on young, sexually active, multiethnic, mainly inner city, female students. The main aim of this paper is to describe our recruitment methods. Secondary aims in two small subgroups, are to compare characteristics of women recruited with those not recruited, and to explore participants' understanding of when their samples would be tested for chlamydia.

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“…Newspaper coverage of the United Kingdom clinical disaster did not alert potential trialists to the "risky world of human subject research," making them wary of similar trials. On the contrary, publicity that unskilled persons could earn £2,500 for "doing nothing" led to a spike in recruitment as would-be trialists sought to cash-in on the windfall money (Atherton, Banks, Harbit, & Oakeshott, 2006;Stobbart et al, 2007; TeGenero monoclonal antibody causes shock, 2006; Will volunteers still want to take part, 2006). Although Abadie's intention is to restrict the number of clinical trial opportunities in the United States and to protect his at-risk population, the sensational title, professional guinea pigs, is as likely to result in more un/underemployed people, not fewer, seeking easy-money recruitment into trials.…”

mentioning

confidence: 99%

Book Review: Roberto Abadie The Professional Guinea Pig: Big Pharma and the Risky World of Human Subjects Durham, NC: Duke University Press 2010. 184 pp. $22.95. ISBN 978-0-8223-4823-8

Tolich

2011

Qual Health Res

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Recruiting young women to a trial of chlamydia screening

Cited by 3 publications

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Maximising retention in a longitudinal study of genital Chlamydia trachomatis among young women in Australia

Maximising retention in a longitudinal study of genital Chlamydia trachomatis among young women in Australia

Recruitment of young women to a trial of chlamydia screening – as easy as it sounds?

Book Review: Roberto Abadie The Professional Guinea Pig: Big Pharma and the Risky World of Human Subjects Durham, NC: Duke University Press 2010. 184 pp. $22.95. ISBN 978-0-8223-4823-8

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