Recovery Prognosis of Aspects in Patients With Acute Anterior Circulation Cerebral Infarction Undergoing Mechanical Thrombectomy

Abstract

Aim: Comparison of the prognostic value of recovery of the ASPECTS score compared with perfusion imaging in patients with acute anterior circulation cerebral infarction undergoing thrombectomy.
 Materials and methods: Retrospective cross-sectional descriptive study combined with a prospective study of 82 cases undergoing CT scan without injection, CTA, and CTP, using RAPID software to calculate core and penumbra values and mechanical thrombectomy within 6-24 hours. Good (0-2 points) and poor (3-6 points) stroke outcomes were assessed at 3 months by the modified Rankin functional recovery score (mRS). Use the ROC curve and AUC value to compare the good and bad stroke prognostic value of ASPECTS and the core, penumbra, mismatch ratio values.
 Results: From January 2022 to May 2023, 82 patients were included in the study. At 90 days, the independent outcome rate of good mRS function (0-2) was 57.3%, and poor mRS function (3-6) was 42.7%. The ROC curve showed that, among the ASPECTS, core, penumbra, and mismatch ratio indices, only ASPECTS could predict stroke outcome well (p = 0.001<0.05), the area under the curve was 0.709 with J - point cutoff index at threshold ASPECTS = 6 with sensitivity 93.6% and specificity 57.1%.
 Conclusion: ASPECTS ≥ 6 can predict good functional recovery after stroke in patients with acute anterior circulation cerebral infarction undergoing thrombectomy at the extended window.