Recovery of renal function after 90 d on dialysis: implications for transplantation in patients with potentially reversible causes of renal failure

Siddiqui, Samira; Norbury, Michael; Robertson, Sue; Almond, Alison; Isles, Chris

doi:10.1111/j.1399-0012.2007.00755.x

Cited by 14 publications

(22 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of those PHD-AKI patients, more than 40% eventually recovered sufficient kidney function to no longer require RRT. This outcome is significantly better than that reported in other studies [18.] A recent article by Cerda et al [19] discussed results from available reports indicating at most a 20% outpatient recovery for D-AKI (depending on the percentage of CKD in the population reported).…”

Section: Discussioncontrasting

confidence: 52%

“…The study was not extended beyond 3 months as primary events such as increased risk of mortality occur mainly during the early period of dialysis-dependent AKI [21,22,23]. This increased mortality risk has been attributed to altered immunological status and ischemia reperfusion injury [18,22,24,25,26]. This high rate of mortality extends even beyond 6 months.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Predictors and Outcomes of Post-Hospitalization Dialysis Dependent Acute Kidney Injury

Gautam

Brooks

Balogun

et al. 2015

Nephron

View full text Add to dashboard Cite

Background: Acute kidney injury (AKI) is a frequent complication of hospitalized patients and is associated with poor outcomes. Hospitalized patients with AKI may need prolonged dialysis, necessitating post-hospitalization dialysis (PHD-AKI). Scarce information is available to stratify the risks and predict outcomes. This study aims to assess outcomes and identify predictors of outcomes of PHD-AKI within 90 days. Methods: All adult AKI patients initiating hemodialysis (HD) at the University of Virginia (UVA) between June 1, 2012, and September 30, 2013 were retrospectively studied. PHD-AKI patients continued treatment at a specifically designated unit. They were followed until an outcome (end-stage renal disease [ESRD], death or dialysis-independence) was achieved. Results: During the study period, 108 patients required outpatient dialysis out of 365 AKI patients initiating in-patient HD at UVA. An additional 11 patients who developed dialysis-requiring AKI at referring hospitals but underwent HD at our unit were included for a total of 119 patients studied. ESRD was declared in 48.7%, while 9.2% expired and 42.0% achieved dialysis independence. Congestive heart failure, baseline renal function and a prior episode of AKI within the preceding 6 months were statistically significant predictors of renal outcomes. Conclusion: Dialysis independence of PHD-AKI patients is not uncommon. Certain clinical parameters may help predict renal outcome. Identifying predictors of renal recovery will guide further interventions, especially with the Centers for Medicare and Medicaid Services soon to allow AKI patients to be dialyzed at outpatient ESRD facilities. Ongoing biomarkers research may add further knowledge for optimum diagnosis and prognosis of AKI.

show abstract

Section: Discussioncontrasting

confidence: 52%

Section: Discussionmentioning

confidence: 99%

Predictors and Outcomes of Post-Hospitalization Dialysis Dependent Acute Kidney Injury

Gautam

Brooks

Balogun

et al. 2015

Nephron

View full text Add to dashboard Cite

show abstract

“…Delayed renal recovery after acute renal failure occurs in Ͻ4% of patients after 90 days of hemodialysis, and allograft recovery after months of ischemia-induced renal failure has not been reported. 12,13 Similarly, although a small fraction of patients (9%-15%) have transient dialysis requirements after endovascular treatment of juxtarenal AAA, renal failure usually occurs immediately postoperatively and typically resolves Յ6 months.…”

Section: Discussionmentioning

confidence: 98%

Revascularization and rescue of a failed kidney transplant in a case of autosomal dominant polycystic kidney disease

Seshadri

Byrne

Kramer

et al. 2012

Journal of Vascular Surgery

View full text Add to dashboard Cite

Autosomal dominant polycystic kidney disease is a cause of end-stage renal disease associated with abdominal aortic aneurysms. We report a patient with autosomal dominant polycystic kidney disease who received an allograft kidney and subsequently underwent treatment of an abdominal aortic aneurysm with aortic ligation and axillary-bifemoral bypass. After years of graft function, bypass thrombosis resulted in dialysis-dependent renal failure. Aortobifemoral bypass resulted in immediate restoration of allograft function despite 6 months of prior renal failure. Aortic reconstruction restored renal function to a hibernating allograft long after clinical graft failure from arterial ischemia, a phenomenon not previously reported in the literature.

show abstract

“…[4][5][6] Predictors of renal recovery are listed in Figure 64.4 and include preserved renal size, evidence of a renal "blush" or nephrogram by imaging, recent loss of GFR, and recent baseline creatinine concentration below 3 mg/dl. 7 Figure 64.5 shows thrombosis of a renal artery within a stent placed 1.5 years previously for atherosclerotic renal artery stenosis in a patient with a single functioning kidney.…”

Section: Thromboembolic Ischemic Renal Diseasementioning

confidence: 99%

Thromboembolic Renovascular Disease

Greco¹,

Dwyer²,

Lewis³

2010

Comprehensive Clinical Nephrology

View full text Add to dashboard Cite

Recovery of renal function after 90 d on dialysis: implications for transplantation in patients with potentially reversible causes of renal failure

Abstract: It may be sensible to postpone transplantation in patients with certain types of renal failure, perhaps particularly patients with renovascular disease who have recently undergone a failed revascularization procedure.

Cited by 14 publications

References 10 publications

Predictors and Outcomes of Post-Hospitalization Dialysis Dependent Acute Kidney Injury

Predictors and Outcomes of Post-Hospitalization Dialysis Dependent Acute Kidney Injury

Revascularization and rescue of a failed kidney transplant in a case of autosomal dominant polycystic kidney disease

Thromboembolic Renovascular Disease

Contact Info

Product

Resources

About