2003
DOI: 10.1016/s0734-9750(02)00050-2
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Recovery of microalgal biomass and metabolites: process options and economics

Abstract: Commercial production of intracellular microalgal metabolites requires the following: (1) largescale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the… Show more

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Cited by 1,858 publications
(765 citation statements)
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References 57 publications
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“…5 Selection of cost-effective technologies for biomass harvesting and drying Given the relatively low biomass concentration obtainable in microalgal cultivation systems due to the limit of light penetration (typically in the range of 1-5 g/L) and the small size of microalgal cells (typically in the range of 2-20 lm in diameter), costs and energy consumption for biomass harvesting are a significant concern needs to be addressed properly. Different technologies, including chemical flocculation, 75 biological flocculation, 76 filtration, 77 centrifugation, 78 and ultrasonic aggregation 79 have been investigated for microalgal biomass harvesting. In general, chemical and biological flocculation require only low operating costs; however, they have the disadvantage of requiring long processing period and having the risk of bioreactive product decomposition.…”
Section: Design Of Advanced Photobioreactorsmentioning
confidence: 99%
“…5 Selection of cost-effective technologies for biomass harvesting and drying Given the relatively low biomass concentration obtainable in microalgal cultivation systems due to the limit of light penetration (typically in the range of 1-5 g/L) and the small size of microalgal cells (typically in the range of 2-20 lm in diameter), costs and energy consumption for biomass harvesting are a significant concern needs to be addressed properly. Different technologies, including chemical flocculation, 75 biological flocculation, 76 filtration, 77 centrifugation, 78 and ultrasonic aggregation 79 have been investigated for microalgal biomass harvesting. In general, chemical and biological flocculation require only low operating costs; however, they have the disadvantage of requiring long processing period and having the risk of bioreactive product decomposition.…”
Section: Design Of Advanced Photobioreactorsmentioning
confidence: 99%
“…Another alternative is using expanded bed adsorption chromatography, which is also used to isolate native potato proteins from potato juice, followed by ultrafiltration to concentrate the protein fractions and remove anti-nutritional factors [72]. The highest component cost is the purification via chromatography, with estimated processing cost of USD 184/kg-product [81]. Consequently this process is only feasible if the product has a high value application, e.g.…”
Section: Latexmentioning
confidence: 99%
“…disk stack, bowl, tubular bowl and scroll discharger) in this study it is considered a disk stack centrifuge (Molina Grima et al, 2003). This step is critical to the economic and sustainability viability of microalgae cultivation, as large energy inputs are required (Mata et al, 2010b).…”
Section: Process Description: Assumptions and Conditionsmentioning
confidence: 99%