Recovery of l-tryptophan from dilute aqueous feed by extractive solvent sublation and solvent extraction methods and optimization

Poddar, Sourav; Khanam, Jasmina

doi:10.1016/j.molliq.2022.118627

Cited by 8 publications

(12 citation statements)

References 28 publications

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“…Cost becomes a major factor when a process handles a large quantity of material. Therefore, there is a commercial interest in finding cost‐effective methods (e.g., solvent sublation method) that can separate smaller biomolecules from fermentation wastewater 8,9 …”

Section: Introductionmentioning

confidence: 99%

“…RSM is a statistical technique for optimizing complex processes because it allows for more efficient and accessible arrangement and interpretation of experiments. Earlier, many investigators applied this method to various bioprocesses 9,30‐33 …”

Section: Introductionmentioning

confidence: 99%

“…Therefore, there is a commercial interest in finding cost-effective methods (e.g., solvent sublation method) that can separate smaller biomolecules from fermentation wastewater. 8,9 Each bioseparation process involves a series of steps that bring about enhanced product cost owing to product loss. Reducing the number of steps in the separation operation is desirable because of the low product yield and product loss associated with serial steps.…”

Section: Introductionmentioning

confidence: 99%

“…This method was later modified into various categories, in which 'solvent sublation' had been widely used to recover organic substance/biomolecules and to treat waste aqueous solution. 9 The solvent sublation method differs from conventional solvent extraction because the stationary solvent layer acts as a 'sink' for the solute. This unique method may be very effective if combined with the reactive extraction technique, consuming less organic solvent and having low energy consumption.…”

Section: Introductionmentioning

confidence: 99%

“…Earlier, many investigators applied this method to various bioprocesses. 9,[30][31][32][33] There is no ready apparatus in the market for this technique, and because of the simplicity of the necessary devices these are tailored according to the task at hand. However, all solvent sublation set-ups include the following basic parts: gas source, gas flow regulating device, gas presaturation flask, and a glass column fitted with a glass frit.…”

Section: Introductionmentioning

confidence: 99%

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Adsorptive bubble separation method in the recovery of a biomolecule

Poddar

Khanam

Pradhan

2022

J of Chemical Tech & Biotech

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The present work aims to separate an amino acid (l-phenylalanine) from a highly dilute aqueous solution by the 'adsorptive bubble separation method'. Separation is based on the principle of adsorption at the interphase of the gas bubble and aqueous phase and subsequent amino acid extraction in the top layered nonaqueous phase. The operation was carried out in a long glass column with a comprehensive solvent chamber at the top. Design-Expert software optimizes the process parameters, and the process involves three variables: gas (nitrogen) flow rate, extractant, and solvent quantity, which control responses, recovery percentage, and the ratio of enrichment. The design models are found to be significant. The maximum recovery of amino acid observed was 75.545% and the value of the enrichment ratio was 3.87. In addition, two models were generated by the software, which was statistically significant (P < 0.05). Therefore, this process is adopted as it is of straightforward construction, eco-friendly, and less costly than other methods previously known to recover l-phenylalanine from a dilute solution.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Adsorptive bubble separation method in the recovery of a biomolecule

Poddar

Khanam

Pradhan

2022

J of Chemical Tech & Biotech

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Maximizing methyl red dye removal efficiency: a targeted parameter approach

Behera,

Poddar,

Byun

2024

J of Chemical Tech & Biotech

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BACKGROUNDLiquid–liquid extraction plays a crucial role in the chemical industry for obtaining valuable products. This research focuses on optimizing key parameters, namely dye removal percentage, solvent capacity, and distribution coefficient, in the liquid–liquid extraction of methyl red dye from its aqueous solution using benzene as the extractant. The study investigates the influence of key variables, including feed dye concentration (20–100) ppm, extraction time (10–30) min and dye solution‐to‐solvent ratio (1–3) mL/mL. The experiments are conducted at a constant pH of 3 and controlled temperatures of (27 ± 2) °C.RESULTSStrategically controlling various parameters, this investigation aims to achieve superior outcomes, surpassing prior achievements in similar experimental conditions. Utilizing the Box‐Behnken design for optimization, the research attains a remarkable recovery efficiency of 84.61%. The achieved optimal values for dye removal, distribution coefficient, and solvent capacity are (84.61±5.07)%, 5.22±0.31, and (5.17±0.94) ppm, respectively, at a feed dye concentration of 20 ppm, an extraction time of 27.994 min, and a dye solution‐to‐solvent ratio of 3 mL/mL.CONCLUSIONThese findings underscore the potential for maximizing methyl red dye extraction efficiency and surpassing previously reported efficiency using the presented parameters with the same input data. The study contributes to advancements in liquid–liquid extraction technology and provides a deeper understanding of the optimization process with technical precision.This article is protected by copyright. All rights reserved.

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