Recovery of citric acid from fermentation broths by electrodialysis with bipolar membranes

Ion-exchange membranes in chemical synthesis – a review

“…However, BMED is the most widely used membrane technique for this purpose, and some pilot and commercial industrial plants are currently under operation worldwide, mostly to recover acids from fermentation broths [18,159]. BMED was also demonstrated to be effective in recovery of lactic acid [160][161][162][163][164][165][166], citric acid [167][168][169][170][171][172]191], fumaric acid [173] from fermentation broth, but also in salts conversion in the following acids: formic acid [174,175], acetic acid [176,177], gluconic acid [172,192], p-toluenesulfonic acid [178], salicylic acid [179], ascorbic acid [180,181], lactobionic acid [182], aminoacids [183] and morpholine [184]. The above processes encounter typical obstacles characteristic of BMED: proton and hydroxyl leakage through monopolar IEMs, and ion leakage through BPM.…”

“…Apart from the membrane technique used, the stack configuration is often crucial for ion transport and for overall process performance: and many different configurations can be applied for production of the compound with different results [170,[190][191][192], as it can minimize the possibility of leakage and contamination [191,193].…”

The extraction of lactic acid by emulsion type of liquid membranes using alamine 336 in escaid 100

“…Due to the increasing cost of crude oil, a common raw material for the chemical synthesis of lactic acid, the efficient production of lactic acid through fermentation has become increasingly important (Hano et al, 1993;Siebold et al, 1995;Drioli et al, 1996;Han et al, 2000;Heewsink et al, 2002). Currently, a number of processes for lactic acid separation without precipitation have been reported such as direct distillation (Vaidya et al, 2005), adsorption (Hano et al, 1993;Novalic et al, 1995;Siebold et al, 1995;Drioli et al, 1996;Han et al, 2000;Heewsink et al, 2002;Vaidya et al, 2005), reactive extraction (Jarvinen et al, 2000;Kilic et al, 2002;Vaidya et al, 2005;Ma et al, 2006), ion exchange (Kilic et al, 2002;Lee et al, 2004;Vaidya et al, 2005;Ataei and Vasheghani-Farahani, 2008), and electrodialysis (Bailly, 2002;Pinacci and Radaelli, 2002). These methods have several disavantages including cost, and require multiple steps, and operate with low efficiency under practical conditions.…”

Separation and concentration of lactic acid by electro-electrodialysis

“…Luo). tion [4], adsorption [4,5], reactive extraction [4,6,7], diffusion dialysis [4,8], ion exchange [1,4,9], esterification distillation [4,10], conventional electrodialysis [11,12], bipolar membrane electrodialysis [13,14], etc. Reactive extraction can selectively remove lactic acid from the fermentation broth, and may combine with the continuous fermentation.…”