Recovery of bioactive compounds from red onion skins using conventional solvent extraction and microwave assisted extraction

Stoica, Florina; Râpeanu, Gabriela; Nistor, Oana Viorela; Enachi, Elena; Stănciuc, Nicoleta; Mureșan, Claudia; Bahrim, Gabriela

doi:10.35219/foodtechnology.2020.2.07

Cited by 6 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Each of the other identified compounds contributed with a concentration lower than 8% of the total anthocyanins content. These observations comply with our previous study, in which the main anthocyanins found in the red onion skins extract were cyanidin 3-O-laminaribioside, cyanidin 3-O-(6 -malonyllaminaribioside), and peonidin 3-O-malonylglucoside [25]. In general, our results are in agreement with the literature data [26], the most commonly reported anthocyanins in the red onion being cyanidin derivatives.…”

Section: Chromatographic Profile Of the Anthocyanins From The Red Onion Skins Extractsupporting

confidence: 93%

See 1 more Smart Citation

Bioactive’s Characterization, Biological Activities, and In Silico Studies of Red Onion (Allium cepa L.) Skin Extracts

Stoica

Aprodu

Enachi

et al. 2021

Plants

Self Cite

View full text Add to dashboard Cite

This study aimed to investigate the thermal stability and biological activities of the phytochemicals from the red onion skins extract, which are a rich source of anthocyanins. Eight anthocyanins were identified in the extract by high-performance liquid chromatography, the most abundant ones being cyanidin 3-O-laminaribioside and cyanidin 3-O-(6″-malonoyl-laminaribioside). The study also involved the assessment of the thermal degradation kinetics of anthocyanins and antioxidant activity in the 75–155 °C temperature range. The thermal degradation kinetics was described using the first-order kinetics model. In terms of thermal stability, increasing the temperature resulted in lower half-life values (t1/2) and higher degradation rate constant values (k) for both anthocyanins and antioxidant activity. The thermodynamic parameters revealed that the phytochemicals’ degradation is a non-spontaneous and endothermic reaction. Furthermore, the inhibitory effect of the extract was investigated against the enzymes affiliated with metabolic syndrome, oxidative stress, and inflammatory process diseases. Thus, we also demonstrated that the red onion skins extract exerted inhibitory activity on α-glucosidase, α-amylase, lipase, and lipoxygenase. Considering the high content of bioactives and various biological properties, the red onion skins extract is suitable for multiple applications.

show abstract

Section: Chromatographic Profile Of the Anthocyanins From The Red Onion Skins Extractsupporting

confidence: 93%

“…The extract was spectrophotometrically described in terms of TAC, TPC, and antioxidant activity, as described by Stoica et al [25]. Thus, 2 mg/mL of extract diluted in ultrapure water were used for the analysis.…”

Section: Extract Characterizationmentioning

confidence: 99%

Bioactive’s Characterization, Biological Activities, and In Silico Studies of Red Onion (Allium cepa L.) Skin Extracts

Stoica

Aprodu

Enachi

et al. 2021

Plants

Self Cite

View full text Add to dashboard Cite

show abstract

“…Nevertheless, a combined method would be an interesting alternative for those cases where cutting time and expenses are essential, such as in quality control laboratories [64]. Furthermore, despite the poorer results, the multi-response method that has been developed in this study achieves greater anthocyanins recoveries than the only other method that has been reported in the literature for the extraction of bioactive compounds from onion using MAE (1.75 ± 0.04 mg C3G/g DW) [29].…”

Section: Multiresponse-optimizationmentioning

confidence: 85%

“…In the revision of the bibliography on this subject, one study where MAE was used as the extraction technique to obtain anthocyanins from onions has been found just [29]. This article investigated how the concentration of the solvents, the acids, the different temperatures, and an array of extraction times had an influence on the extraction of the anthocyanins.…”

Section: Introductionmentioning

confidence: 99%

Extraction of Antioxidant Compounds from Onion Bulb (Allium cepa L.) Using Individual and Simultaneous Microwave-Assisted Extraction Methods

et al. 2022

View full text Add to dashboard Cite

Despite the excellent beneficial properties that anthocyanins and total phenolic compounds give to the red onion bulbs, few articles have investigated modern extraction techniques or experimental designs in this field. For this reason, the present study proposes the development and optimization of alternative methods for the extraction of these compounds based on microwave-assisted extraction and the Box-Behnken experiment design. The optimal values for the extraction of total anthocyanins have been established at 62% methanol composition as a solvent, pH 2, 56 °C temperature, and 0.2:13 g:mL sample-solvent ratio. Regarding the extraction of total phenolic compounds, the optimal conditions have been established at 100% pure methanol as a solvent with pH 2, 57 °C temperature, and 0.2:8.8 g:mL sample-solvent ratio. Short extraction times (min), good recoveries (mg of bioactive compound g−1 of dry onion), and high repeatability and intermediate precision (coefficient of variation (%)) have been confirmed for both methods. Regarding total anthocyanins, the following results have been obtained: 2 min, 2.64 ± 0.093 mg of total anthocyanins g−1 of dry onion, and 2.51% and 3.12% for precision. Regarding phenolic compounds, the following results have been obtained: 15 min, 7.95 ± 0.084 mg of total phenolic compound g−1 of dry onion, and 3.62% and 4.56% for precision. Comparing these results with those of other authors and with those obtained in a previous study of ultrasound-assisted extraction, it can be confirmed that microwave-assisted extraction is a quantitative, repeatable, and very promising method for the extraction of phenolic compounds and anthocyanins, which offers similar and even superior results with little solvent expense, time, and costs.

show abstract

“…Similar levels of 90.07 mg GAE g −1 DM were attained with ultrasoundassisted aqueous glycerol extraction [10], but, significantly, a higher yield (137.50 mg caffeic acid equivalents g −1 DM) has been reported for OSW extraction with a glycerol/sodium propionate deep eutectic solvent [11]. The use of hydroethanolic solvents at ambient temperature has been shown to afford Y TP levels of approximately 81.48-93.42 mg GAE g −1 DM [29,30]. However, the range of total polyphenols in OSW may vary largely, from 14.55 to 288.74 mg GAE g −1 DM [31].…”

Section: Process Optimization-extraction Efficiencymentioning

confidence: 99%

Glycerol-Based Deep Eutectic Solvents for Simultaneous Organosolv Treatment/Extraction: High-Performance Recovery of Antioxidant Polyphenols from Onion Solid Wastes

et al. 2022

View full text Add to dashboard Cite

Onion solid wastes (OSW) are a food side-stream with high polyphenolic load and distinguished polyphenolic profile. This study was conducted in order to explore a novel methodology of production of polyphenol-enriched extracts with antioxidant properties from OSW, using glycerol and green deep eutectic solvents (DES), composed of glycerol/citric acid and glycerol/sodium acetate. The organosolv process developed was appraised by establishing models based on severity, but also response surface methodology. Using a linear model, it was, for the first time, proposed that there is a direct correlation between the yield of the process in total polyphenols and the combined severity factor. Furthermore, response surface optimization enabled the establishment of linear models to predict the effects of time and temperature on the total polyphenol extraction yield. Out of the solvents tested, the DES composed of citric acid and glycerol was found to provide the highest yield in total polyphenols (87.90 ± 3.08 mg gallic acid equivalents per g dry mass) at significantly higher combined severity. However, the extraction efficiency of this solvent was virtually equal to that of the two other solvents tested. On the other hand, the polyphenolic composition of the extract obtained with the glycerol/citric acid DES was characterized by exceptionally high quercetin concentration. This extract also displayed the highest antioxidant activity. Based on the evidence emerged, it was proposed that OSW polyphenol extraction with the DES glycerol/citric acid could be used for production of extracts enriched in the bioactive flavonoid quercetin, with enhanced antioxidant activity. Moreover, using this green methodology, 27.59 ± 0.09 g of pure quercetin could be recovered out of 1 kg OSW. Thus, this methodology could be employed as a sustainable means of producing quercetin, through valorization of food wastes in a biorefinery context.

show abstract

Recovery of bioactive compounds from red onion skins using conventional solvent extraction and microwave assisted extraction

Cited by 6 publications

References 0 publications

Bioactive’s Characterization, Biological Activities, and In Silico Studies of Red Onion (Allium cepa L.) Skin Extracts

Bioactive’s Characterization, Biological Activities, and In Silico Studies of Red Onion (Allium cepa L.) Skin Extracts

Extraction of Antioxidant Compounds from Onion Bulb (Allium cepa L.) Using Individual and Simultaneous Microwave-Assisted Extraction Methods

Glycerol-Based Deep Eutectic Solvents for Simultaneous Organosolv Treatment/Extraction: High-Performance Recovery of Antioxidant Polyphenols from Onion Solid Wastes

Contact Info

Product

Resources

About