Recovery of acetaminophen from aqueous solutions using a supported liquid membrane based on a quaternary ammonium salt as ionophore

Abstract

A flat sheet-supported liquid membrane (FSSLM) system, consisting of an ionic liquid, tricapryl-methylammonium chloride (Aliquat 336®) in octan-2-ol, is proposed as a means of recovering acetaminophen (Ac) from aqueous solutions; Ac is an active ingredient widely used in many pharmaceutical preparations. Several parameters which could affect the transport efficiency were examined, i.e., the strippant nature and concentration in the receiving solution, the diluent nature, carrier concentration, initial acetaminophen concentration in the feed solution, and the polymeric support type. A facilitated transport was obtained by impregnating the polymeric support with 10 vol. % of Aliquat 336® in octan-2-ol, 1 M NaOH as a receiving solution, and a feed solution of Ac dissolved in ultrapure water. The study was completed by using the FSSLM thus developed for extracting Ac from some drugs in frequent use in Tunisia (Analgan®, Doliprane®, and Fervex®).

Single-layer membranes for organic solvent nanofiltration: a molecular dynamics simulation and comparative experimental study

“…† In the process of using acetaminophen, a large number of acetaminophen will be mixed into methanol solvents, but there is still no effective method to extract and recover it. 45 …”

“…† In the process of using acetaminophen, a large number of acetaminophen will be mixed into methanol solvents, but there is still no effective method to extract and recover it. 45 Based on the calculation, the membranes (S_0.6 and Mo_0.7) can completely reject acetaminophen in all six solvents, and the solvent permeability was calculated using P S ¼ J S /DP when acetaminophen was present (Table 1). The permeability of the solvent decreases slightly when adding acetaminophen.…”

An Ionic Supported Liquid Membrane for the Recovery of Bisphenol A from Aqueous Solution

“…where 𝑑 , 𝜏 , and 𝜖 represent the membrane thickness, tortuosity, and porosity, respectively. The normalized flux values of BPA were compared to those obtained for salicylic acid [53] and acetaminophen [54] using polypropylene (Accurel ® PP 2E-HF) and polyvinylidene difluoride as the polymeric support.…”

“…The normalized flux values of BPA were compared to those obtained for salicylic acid [53] and acetaminophen [54] using polypropylene (Accurel ® PP 2E-HF) and polyvinylidene difluoride as the polymeric support. J N (10 −6 mol m −2 s −1 ) 0.43 [54] 4 [54] The results illustrated in Figure 12 proved that the polymeric support 2E-PP displayed the best performance for the transport of BPA, with an acceptable R% value of 89%. Additionally, the polymeric support PP and PVDF exhibited lower values of BPA that were recovered in the stripping phase after 8 h of transport.…”

Ibuprofen Recovery from Aqueous Solutions by Supported Liquid Membranes

“…The advantages to use this technique (SLM) are that the extraction and stripping of the species is performed in one step, the volume of organic components is very small thus the pollution is very low, it is easy to scaleup, etc [28,29]. The applications of SLMs include the recovery of metals and ions from effluents (Ni(II), Cu(II), Zn(II), Hg(II), Cd(II), Cr (VI), Pt(IV), Pd (II)) [29][30][31][32][33][34], of organic acids like citric acid [35], of drugs (cephalexin, macrolides, acetaminophen) [36][37][38], and as concentration method [39].…”