“…Groundbreaking studies in the 1960s, 1970s, and 1980s provided mostly descriptive data on the natural history of drug abuse with samples drawn from drug abuse treatment and the criminal justice system. 9,12,22,[38][39][40][41][42][43][44][45][46] Natural recovery is less well studied, 11,13,14,31,47 especially recently, and data are sparse on the factors associated with sustained heroin cessation, particularly among street-recruited samples. The CHANGE Study focused on cessation of heroin use specifically, as opposed to cessation of all drugs or cessation of drug injection for three primary reasons.…”