Recovery from aphasia following brain injury: the role of reorganization

Marsh, Elisabeth B.; Hillis, Argye E.

doi:10.1016/s0079-6123(06)57009-8

Cited by 58 publications

(72 citation statements)

References 74 publications

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“…In the course of deafness, we observed a growing phonological implication of the right PSTG/SMG, whereas the implication of the left PSTG/ SMG in sound imagery decreased. Transcallosal disinhibition is an adaptive behavior that is frequently reported after left strokes [Marsh and Hillis, 2006]; if contralateral compensation resulted from bilateral interhemispheric disinhibition following the declining efficiency of both PSTG/ SMG, we should not observe this asymmetry, but instead a bilateral positive correlation with deafness (either with the duration of hearing loss or of auditory deprivation). We therefore conclude that the remarkable involvement of the right PSTG/SMG in phonological processing resulted from specific cognitive factors, i.e., the need to maintain phonological processing for visual communication, such as in speech-reading [Lazard et al, 2010b;Mortensen et al, 2006;Suh et al, 2009].…”

Section: Discussionmentioning

confidence: 91%

“…As most cognitive functions are asymmetrically implemented in the brain [Formisano et al, 2008;Hickok and Poeppel, 2007;Hugdahl, 2000], the engagement of the contralateral cortex may be less efficient than the primary functional organization, and hence maladaptive [Kell et al, 2009;Marsh and Hillis, 2006;Martin and Ayala, 2004;Naeser et al, 2005;Preibisch et al, 2003;van Oers et al, 2010].…”

Section: Introductionmentioning

confidence: 99%

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Bilateral reorganization of posterior temporal cortices in post‐lingual deafness and its relation to cochlear implant outcome

Lazard

Lee

Truy

et al. 2012

Human Brain Mapping

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Post-lingual deafness induces a decline in the ability to process phonological sounds or evoke phonological representations. This decline is paralleled with abnormally high neural activity in the right posterior superior temporal gyrus/supramarginal gyrus (PSTG/SMG). As this neural plasticity negatively relates to cochlear implantation (CI) success, it appears important to understand its determinants. We addressed the neuro-functional mechanisms underlying this maladaptive phenomenon using behavioral and functional magnetic resonance imaging (fMRI) data acquired in 10 normal-hearing subjects and 10 post-lingual deaf candidates for CI. We compared two memory tasks where subjects had to evoke phonological (speech) and environmental sound representations from visually presented items. We observed dissociations in the dynamics of right versus left PSTG/SMG neural responses as a function of duration of deafness. Responses in the left PSTG/SMG to phonological processing and responses in the right PSTG/ SMG to environmental sound imagery both declined. However, abnormally high neural activity was observed in response to phonological visual items in the right PSTG/SMG, i.e., contralateral to the zone where phonological activity decreased. In contrast, no such responses (overactivation) were observed in the left PSTG/SMG in response to environmental sounds. This asymmetry in functional adaptation to deafness suggests that maladaptive reorganization of the right PSTG/SMG region is not due to balanced hemispheric interaction, but to a specific take-over of the right PSTG/SMG region by phonological processing, presumably because speech remains behaviorally more relevant to communication than the processing of environmental sounds. These results demonstrate that cognitive long-term alteration of auditory processing shapes functional cerebral reorganization. Hum Brain Mapp 00:000-000,

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Section: Discussionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Bilateral reorganization of posterior temporal cortices in post‐lingual deafness and its relation to cochlear implant outcome

Lazard

Lee

Truy

et al. 2012

Human Brain Mapping

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“…Answering these questions could help with the development of appropriate language rehabilitation methods and thus have benefits for clinical practice. Previous reports on the role of the nondominant hemisphere after injury have produced controversial and inconsistent results (Marsh et al, 2006;Crosson et al, 2009). According to some authors, the participation of the nondominant hemisphere is required during reorganization (Calvert et al, 2000;Crinion and Price, 2005;Pulvermüller et al, 2005;Jensen et al, 2011) at least during the early stages of recovery (Knopman et al, 1983;Weiller et al, 1995;Elkana et al, 2011).…”

Section: Laterality Indexmentioning

confidence: 99%

What do patients with epilepsy tell us about language dynamics? A review of fMRI studies

Baciu

Perrone‐Bertolotti

2015

Reviews in the Neurosciences

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AbstractThe objective of this review is to resume major neuroimaging findings on language organization and plasticity in patients with focal and refractory epilepsy, to discuss the effect of modulatory variables that should be considered alongside patterns of reorganization, and to propose possible models of language reorganization. The focal and refractory epilepsy provides a real opportunity to investigate various types of language reorganization in different conditions. The ‘chronic’ condition (induced by the epileptogenic zone or EZ) is associated with either recruitment of homologous regions of the opposite hemisphere or recruitment of intrahemispheric, nonlinguistic regions. In the ‘acute’ condition (neurosurgery and EZ resection), the initial interhemispheric shift (induced by the chronic EZ) could follow a reverse direction, back to the initial hemisphere. These different patterns depend on several modulatory factors and are associated with various levels of language performance. As a neuroimaging tool, functional magnetic resonance imaging enables the detailed investigation of both hemispheres simultaneously and allows for comparison with healthy controls, potentially creating a more comprehensive and more realistic picture of brain-language relations. Importantly, functional neuroimaging approaches demonstrate a good degree of concordance on a theoretical level, but also a considerable degree of individual variability, attesting to the clinical importance with these methods to establish, empirically, language localization in individual patients. Overall, the unique features of epilepsy, combined with ongoing advances in technology, promise further improvement in understanding of language substrate.

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“…There were differences between individuals in the initial value of total energy expenditure and cognitive FIM, as shown in Table 1, the initial value of total energy expenditure ranging from 1133 to 2762 kcal, and the initial value of cognitive FIM ranging widely from 6 to 34. This was because cognitive function in the moderate to severe stroke group would have been affected by the complicated reconstruction of the nervous system that occurred in the recovery phase, and in some cases consciousness disorder and language dysfunction remained (Marsh et al, 2006). Moreover, it is considered that there were differences between individuals in the initial value of cognitive FIM.…”

Section: Discussionmentioning

confidence: 99%

The Association between Total Energy Expenditure and Cognitive Function in Convalescent Patients with Cerebrovascular Disease*

Kojima

Nagano

2018

Int. J. Sport Health Sci.

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(Abstract) [Objective] It has been reported that everyday physical activity, exercise, and physical fitness in older adults can affect their cognitive function. However, to our knowledge, no empirical evidence of this effect has yet been reported in convalescent patients with cognitive impairment resulting from cerebrovascular disease. Therefore, for such patients, it is important to investigate this issue to ensure optimal amelioration of their cognitive impairment during rehabilitation.The aim of this study was to estimate the amount of total energy expenditure during hospitalization, and to investigate the association between total energy expenditure and cognitive function in convalescent patients with cerebrovascular [Results] Both total energy expenditure and cognitive items on the FIM increased significantly (p<0.001) during the five-month period. A significant correlation was found between them (r=0.294, p=0.001), and the two showed a significant partial correlation (r=0.221, p=0.016) when weight was used as a control variable. There was also a significant partial correlation between the gain in total energy expenditure and the gain in the cognitive items on the FIM when the baseline score for cognitive function was used as a control variable (3 months: r=0.466, p=0.044; 5 months: r=0.485, p=0.035).[Discussion] We conclude that there is a relationship between total energy expenditure and cognitive function in convalescent patients with cerebrovascular disease.

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Recovery from aphasia following brain injury: the role of reorganization

Cited by 58 publications

References 74 publications

Bilateral reorganization of posterior temporal cortices in post‐lingual deafness and its relation to cochlear implant outcome

Bilateral reorganization of posterior temporal cortices in post‐lingual deafness and its relation to cochlear implant outcome

What do patients with epilepsy tell us about language dynamics? A review of fMRI studies

The Association between Total Energy Expenditure and Cognitive Function in Convalescent Patients with Cerebrovascular Disease*

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