Reconstructive Methodology in the Synthesis of 2-Aminopurine
Artyom O. Neymash,
Evgeny N. Ulomsky,
Victor V. Fedotov
et al.
Abstract:A fundamentally new synthetic approach to the synthesis of 2-aminopurine has been developed. It consists in the combination of the creation of a condensed polyazotic heterocyclic tetrazolopyrimidine structure, its transformation into triaminopyrimidine, and its subsequent cyclization into 2-aminopurine. The structure of the obtained compounds was established based on spectral characteristics, and the structure of the intermediate compound 5 was established directly by X-ray diffraction analysis.
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