Reconstructive elasticity imaging for large deformations

Skovoroda, A.R.; Lubinski, L.A.; Emelianov, Stanislav; O’Donnell, Matthew

doi:10.1109/58.764839

Cited by 79 publications

(78 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is also important to recognize that, while other imaging modalities may be used [36] to generate the data needed for reconstructive elasticity imaging, ultrasound has shown tremendous potential through several earlyphase investigations [30,[37][38][39][40] . Another important consideration is that previous peripheral vascular strain im- aging has had limited strain dynamic range since arterial wall deformations only exhibit small strains under physiologic pressures.…”

Section: Discussionmentioning

confidence: 99%

Renal Advances in Ultrasound Elasticity Imaging: Measuring the Compliance of Arteries and Kidneys in End-Stage Renal Disease

et al. 2005

View full text Add to dashboard Cite

Background/Aims: Ultrasound elasticity imaging visually represents tissue hardness measurements using high-resolution ultrasound speckle-tracking algorithms. This method has recently been applied in the renal setting to measure arterial compliance in end-stage renal disease (ESRD) and the mechanical properties of transplant kidneys in vivo. Methods: Ultrasound radio-frequency signal measurements were made of the brachial artery in 5 ESRD subjects and 5 healthy controls and renal transplant measurements in 2 subjects, 1 with chronic allograft nephropathy (CAN) and 1 with normal graft function. Results: Maximal brachial artery percent strain measurements for healthy controls were 32.9 ± 10.2% (mean ± SD) and for ESRD subjects maximal percent strains were 4.9 ± 1.8%. Transplant renal cortical strain for the subject with CAN was approximately one third that of the healthy transplant recipient. Conclusion: Ultrasound elasticity imaging offers the potential to noninvasively measure the mechanical properties of structures within the body.

show abstract

Section: Discussionmentioning

confidence: 99%

Renal Advances in Ultrasound Elasticity Imaging: Measuring the Compliance of Arteries and Kidneys in End-Stage Renal Disease

et al. 2005

View full text Add to dashboard Cite

show abstract

“…The axial gradients of the displacements could then be calculated for estimation of the local strains. Recently, research has been undertaken into the applications of this imaging technique (KALLEL et al, 1998), improvement of the strain estimation algorithm (SKOVORODA et al, 1999;BAIet al, 1999) and extending the elasticity imaging to microscopic level (COHN et al, 1997a;.…”

Section: Introductionmentioning

confidence: 99%

Measurement of the layered compressive properties of trypsintreated articular cartilage: An ultrasound investigation

Zheng

Ding

Bai

et al. 2001

Med. Biol. Eng. Comput.

View full text Add to dashboard Cite

An ultrasound-compression system has been developed for the study of the layered biomechanical properties of articular cartilage. Cartilage specimens harvested from the bovine patella groove, with and without trypsin digestion, were tested using this system. It was noted that a large ultrasound reflection can be detected in the interface of the trypsin digestion front. This ultrasound reflection signal was used to differentiate the deformations of different portions of the cartilage throughout its depth when a load was applied. The equilibrium compression moduli of the digested, undigested and entire portions of articular cartilage were measured. The modulus of the cartilage without any digestion was 660+/-230 kPa. After 1h digestion with 1 mg ml(-1) trypsin solution, the thickness of the digested portion was 0.50+/-0.06m, and the modulus of the entire cartilage layer changed to 125+/-42kPa. The moduli of the digested and undigested portions were 58+/-24 kPa and 470+/-31 kPa, respectively. Similar results were obtained for the cartilage with trypsin digestion for 2 h.

show abstract

“…On the way of the wave propagation, when the stiffness of tissue changes, the wave changes its parameters, such as wavelength. So from the wave images of the tissue, the change of the tissue stiffness can be detected, and the map of the tissue elasticity can be calculated via elasticity reconstruction algorithms [18][19][20][21][22][23] .For MRE, the actuator is an important hardware for the technique. Firstly, it should be electro-magnetically compatible (EMC) with the MR scanner, in order not to affect MR imaging process; secondly, it should be easy and flexible to be placed in the scanner's bore, in order to facilitate the application of the MRE technique.…”

mentioning

confidence: 99%

Imaging mechanical shear waves induced by piezoelectric ceramics in magnetic resonance elastography

2006

View full text Add to dashboard Cite

Magnetic Resonance Elastography (MRE) is a noninvasive technique to measure elasticity of tissues in vivo. In this paper, a mechanical shear wave MR imaging system experiment is set for MRE. A novel actuator is proposed to generate mechanical shear waves propagating inside a gel phantom. The actuator is made of piezoelectric ceramics, and fixed on a plexiglass bracket. Both of the gel phantom and the actuator are put into a head coil inside the MR scanner's bore. The actuator works synchronously with an MR imaging sequence running on the MR scanner. The sequence is modified from a FLASH sequence into a motion-sensitizing phasecontrast sequence for shear wave MR imaging. Shear wave images are presented, and these effects on the shear wave MR imaging system, including the stiffness of phantoms, the frequency of the actuator, the parameters of the motion-sensitizing gradient, and the oscillation of the patient bed, are discussed.MRI is a noninvasive medical imaging modality for stimulating the development of medical diagnosis technology. Scientists and engineers are now trying to extend the use of traditional MRI scanner to a wider field. The magnetic resonance elastography (MRE) technique is one of the instances [1] . It is one of the several medical elasticity imaging methods including ultrasound elastography [2 -5] , optical elastography [6,7] . MRE is an analog to the palpation, which has been used by doctors for thousands of years, and is still used now in modern hospitals as a very useful technique to detect diseases such as breast diseases. Doctors use palpation to detect manually the changes of biomechanical properties of pathological tissues. It is proved that the biomechanical properties, such as shear modulus and Yong's modulus can serve as parameters to detect diseases such as breast cancer. For example, the Yong's modulus of pathological tissues are obviously larger than that of normal tissues [8] . The advantages of MRE are that the technique can evaluate the biomechanical properties of tissues quantitatively but not by experience, and can enable us to observe the tissues inside the body profoundly that cannot be palpated by doctors. MRE is proposed to be a very potential technique in medical diagnosis, especially for breast diseases [9][10][11][12][13] . The other medical application fields of MRE include the muscle [14][15][16] and the prostate [17] diseases diagnosis. MRE needs to be implemented via an MRI scanner. An additional mechanical oscillation actuator is always set on the surface of the tissue, and the waves produced by that oscillation will spread from the surface to the inner, which is to be imaged via the MRI scanner. On the way of the wave propagation, when the stiffness of tissue changes, the wave changes its parameters, such as wavelength. So from the wave images of the tissue, the change of the tissue stiffness can be detected, and the map of the tissue elasticity can be calculated via elasticity reconstruction algorithms [18][19][20][21][22][23] .For MRE, the actuator is an importa...

show abstract

Reconstructive elasticity imaging for large deformations

Cited by 79 publications

References 28 publications

Renal Advances in Ultrasound Elasticity Imaging: Measuring the Compliance of Arteries and Kidneys in End-Stage Renal Disease

Renal Advances in Ultrasound Elasticity Imaging: Measuring the Compliance of Arteries and Kidneys in End-Stage Renal Disease

Measurement of the layered compressive properties of trypsintreated articular cartilage: An ultrasound investigation

Imaging mechanical shear waves induced by piezoelectric ceramics in magnetic resonance elastography

Contact Info

Product

Resources

About