Reconstruction of the Frank vectorcardiogram from standard electrocardiographic leads: diagnostic comparison of different methods

Kors, Jan A.; Herpen, Gerard van; Sittig, A. C.; Bemmel, Jan H. van

doi:10.1093/oxfordjournals.eurheartj.a059647

Cited by 350 publications

(249 citation statements)

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“…We chose to do so because true VCG electrodes are rarely used in recent literature. Among all methods to estimate a VCG from a 12-lead ECG, the Kors matrix is the most accurate [23,24].…”

Section: Limitationsmentioning

confidence: 99%

An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects

Nguyên¹,

Potse²,

Regoli³

et al. 2015

Journal of Electrocardiology

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Aim: The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters. Methods: Patient-tailored models based on five heart-failure patients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30°around the anteroposterior axis. Precordial electrodes were shifted 3 cm down.Results: Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (− 6% to + 10%) and QRS-T angle (− 6% to + 3%), but considerable for QRS amplitude (− 36% to + 59%), QRS area (− 37% to + 42%), T-wave amplitude (− 41% to + 36%), and T-wave area (− 42% to + 33%). Conclusion:The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.

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“…We chose to do so because true VCG electrodes are rarely used in recent literature. Among all methods to estimate a VCG from a 12-lead ECG, the Kors matrix is the most accurate [23,24].…”

Section: Limitationsmentioning

confidence: 99%

An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects

Nguyên¹,

Potse²,

Regoli³

et al. 2015

Journal of Electrocardiology

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“…Standard 10-second ECGs were stored in an 8-lead (I, II, II, V1-V6), 5000 sample comma-separated-value file. The Kors matrix was used to calculate vector cardiograms (VCG) from the eight independent ECG leads (22). ECGs and VCGs were analyzed using the automatic MATLAB-based (The MathWorks, Natick, MA) program BEATS and the semiautomatic program LEADS (23,24).…”

Section: Established and Novel Measures Of Sympathetic Activationmentioning

confidence: 99%

Body fat, especially visceral fat, is associated with electrocardiographic measures of sympathetic activation

Hillebrand

Mutsert

Christen

et al. 2014

Obesity

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Objective: Obesity is associated with sympathetic activation, but the role of different fat depots is unclear. The association between body fat, specifically visceral fat, and electrocardiographic measures of sympathetic activation in a population with structurally normal hearts was investigated. Methods: In this cross-sectional baseline analysis of the Netherlands Epidemiology of Obesity study, body fat percentage was assessed with BIA and abdominal subcutaneous (SAT) and visceral adipose tissue (VAT) with magnetic resonance (MR) imaging. Mean heart rate (HR) and five other electrocardiographic measures of sympathetic activation were calculated. We performed multivariate linear regression analyses. Results: In 868 participants with a mean age(SD) of 55(6) years, BMI of 26(4) kg/m 2 , 47% men, body fat was associated with HR and two other measures of sympathetic activation. Per sex-specific SD total body fat, the difference in HR was 1.9 beats/min (95% CI: 1.0, 2.9; P < 0.001) and per SD waist circumference 2.1 beats/min (95% CI: 1.3, 2.9; P < 0.001). The difference in HR per SD VAT was 2.1 beats/min (95% CI: 1.3, 3.0; P < 0.001). Conclusions: Body fat, especially visceral fat, was associated with electrocardiographic measures of sympathetic activation. Our study implies that already before the onset of cardiovascular disease, excess (visceral) body fat is associated with sympathetic activation.

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“…To derive T-loop descriptors, orthogonal X, Y, and 2 leads were reconstructed from the standard 12 ECG leads.15, 259 26 From the spatial T loop and its projection on the frontal (XU) plane, the following parameters were automatically calculated: the amplitude of the maximum T vector (T amplitude) and the angle between the maximum T vector and X axis (Tangle).…”

Section: Twelve-lead Vectorcardiogrammentioning

confidence: 99%

Changes of the t‐wave amplitude and angle: An early marker of altered ventricular repolarization in hypertension

Dilaveris

Gialafos

Poloniecki

et al. 2000

Clinical Cardiology

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summaryBackground: The heterogeneity of ventricular repolarization is an important promhythmic factor. QT dispersion has been proposed to reflect the inhomogeneity of ventricular repolarization, but a poor reproducibility limits its clinical applicability. Reliable noninvasive methods to quantlfy abnormalities in ventricular repolarization are still lacking. The T-loop morphology analysis is a novel method aimed at quantifying ventricular repolarization.Hypothesis: To test the ability of the T-loop morphology analysis to discriminate between hypertensive patients and healthy subjects, 105 hypertensive patients (mean age 63.6 +-12.3 years) and 110 healthy controls (mean age 49.7 f 14.3 years) were evaluated. Methods:The maximum QT interval (QT maximum), the minimum QT interval (QT minimum), and their difference (QT dispersion) were calculated from a digitally recorded 12-lead electrocardiogram (ECG) in both study groups. X, Y, and Z leads were reconstructed from the 12-lead ECG, and the amplitude of the maximum T vector (T amplitude) and the angle between the maximum T vector and X axis (Tangle) were calculated from the projection of the T loop in the frontal plane.

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Reconstruction of the Frank vectorcardiogram from standard electrocardiographic leads: diagnostic comparison of different methods

Cited by 350 publications

References 0 publications

An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects

An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects

Body fat, especially visceral fat, is associated with electrocardiographic measures of sympathetic activation

Changes of the t‐wave amplitude and angle: An early marker of altered ventricular repolarization in hypertension

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